CAJ | 학술논문

目的探讨应用双水平无创正压通气(BiPAP)在慢性阻塞性肺疾病(COPD)合并呼吸衰竭与常规呼吸内科治疗的疗效对比.方法将90例入选患者随机分为治疗与对照两组,每组45例,在常规治疗(包括抗感染、祛痰、平喘、对症纠正电解质紊乱和酸碱平衡失调以及营养支持等治疗,并酌情给予糖皮质激素等)基础上,治疗组加用双水平无创正压通气治疗,3d为1个治疗阶段,观察患者3d后的症状体征及pH值、二氧化碳分压、氧分压、心率指标变化,并与对照组在血气分析各数值间做统计学分析.结果 BiPAP治疗组患者临床症状、体征和血气指标在治疗后较治疗前有明显改善,与对照组相比差异有统计学意义(P均＜0.05).结论 BiPAP通气支持治疗COPD合并呼吸衰竭疗效显著.
목적 탐토응용쌍수평무창정압통기(BiPAP)재만성조새성폐질병(COPD)합병호흡쇠갈여상규호흡내과치료적료효대비.방법 장90례입선환자수궤분위치료여대조량조,매조45례,재상규치료(포괄항감염、거담、평천、대증규정전해질문란화산감평형실조이급영양지지등치료,병작정급여당피질격소등)기출상,치료조가용쌍수평무창정압통기치료,3d위1개치료계단,관찰환자3d후적증상체정급pH치、이양화탄분압、양분압、심솔지표변화,병여대조조재혈기분석각수치간주통계학분석.결과 BiPAP치료조환자림상증상、체정화혈기지표재치료후교치료전유명현개선,여대조조상비차이유통계학의의(P균＜0.05).결론 BiPAP통기지지치료COPD합병호흡쇠갈료효현저.
Objective To compare the effect of bi - level positive airway pressure ventilation in chronic obstructive pulmonary disease (COPD) with respiratory failure and the therapeutic effect of conventional method. Methods Ninety patients selected were randomly divided into treatment and control groups,45 cases in each group.The conventional treatment (including anti -infection,expectorant,asthma,symptomatic correction of electrolyte disorders and acid - base imbalance and nutritional support treatment,and when necessary given corticosteroids,etc.) was the same,treatment group were given bi -level positive airway pressure treatment,3 days for a treatment period,patients were observed for 3 days of the signs and symptoms and pH,PCO2,PO2,HR index changes,and with the control group made between the values of blood gas analysis of the statistical analysis.Results Of clinical symptoms in patients treated with BiPAP,signs and blood gas analysis after treatment than before treatment had significantly improved.Compared with the control group,there were significant differences (P ＜ 0.05).Conclusions The effect of BiPAP ventilatory support for treating COPD with respiratory failure is good.