国际医药卫生导报
國際醫藥衛生導報
국제의약위생도보
INTERNATIONAL MEDICINE & HEALTH GUIDANCE NEWS
2011年
17期
2151-2153
,共3页
二甲双胍%易善复%非酒精性脂肪肝
二甲雙胍%易善複%非酒精性脂肪肝
이갑쌍고%역선복%비주정성지방간
Metformin%Essentiale%Clarithromycin%Nonalcoholic fatty liver disease
目的 探讨二甲双胍联合易善复治疗非酒精性脂肪肝的临床效果。方法 130例非酒精性脂肪肝患者作为研究对象被随机分为实验组和对照组，两组均给予常规治疗，对照组加用易善复，实验组加用二甲双胍联合易善复。结果 实验组显效率(70.77％)显著优于对照组(50.77％)（x 2=4.646,P＜ 0.05）,总有效率(96.92％)优于对照组(87.69％)，但差异无显著性（x z =2.708，P＞0.05）。结论 二甲双胍联合易善复，可显著提高NAFLD治疗效果，改善患者生活质量，值得临床进一步研究。
目的 探討二甲雙胍聯閤易善複治療非酒精性脂肪肝的臨床效果。方法 130例非酒精性脂肪肝患者作為研究對象被隨機分為實驗組和對照組，兩組均給予常規治療，對照組加用易善複，實驗組加用二甲雙胍聯閤易善複。結果 實驗組顯效率(70.77％)顯著優于對照組(50.77％)（x 2=4.646,P＜ 0.05）,總有效率(96.92％)優于對照組(87.69％)，但差異無顯著性（x z =2.708，P＞0.05）。結論 二甲雙胍聯閤易善複，可顯著提高NAFLD治療效果，改善患者生活質量，值得臨床進一步研究。
목적 탐토이갑쌍고연합역선복치료비주정성지방간적림상효과。방법 130례비주정성지방간환자작위연구대상피수궤분위실험조화대조조，량조균급여상규치료，대조조가용역선복，실험조가용이갑쌍고연합역선복。결과 실험조현효솔(70.77％)현저우우대조조(50.77％)（x 2=4.646,P＜ 0.05）,총유효솔(96.92％)우우대조조(87.69％)，단차이무현저성（x z =2.708，P＞0.05）。결론 이갑쌍고연합역선복，가현저제고NAFLD치료효과，개선환자생활질량，치득림상진일보연구。
Objective To explore the efficacy of combination therapy with metformin and essentiale for nonalcoholic fatty liver disease. Methods 130 patients were randomly assigned to receive conventional treatment plus either essentiale alone ( control group )or metformin combined with essentiale ( study group ). Results The study group was markedly superior to the control group in the response rate ( 70.77％ vs. 50.77％; x2= 4.646, P＜ 0.05 ). The overall effectiveness rate was better in the study group than in the control group ( 96.92％ vs. 87.69％ ), but there was no significant difference ( x 2 = 2.708, P ＞ 0.05 ). Conclusions Combination therapy with metformin and essentiale can significantly enhance the efficacy in the treatment of nonalcoholic fatty liver disease and improve quality of life in patients. It is worth studying further in clinical practice.
