中华预防医学杂志
中華預防醫學雜誌
중화예방의학잡지
CHINESE JOURNAL OF
2008年
z1期
128-131
,共4页
林玉娣%董美华%钱燕华%沈洪兵%陈峰%邓于%王旭雯%丁茂金%张雪峰%顾静%王均琴%邵洁
林玉娣%董美華%錢燕華%瀋洪兵%陳峰%鄧于%王旭雯%丁茂金%張雪峰%顧靜%王均琴%邵潔
림옥제%동미화%전연화%침홍병%진봉%산우%왕욱문%정무금%장설봉%고정%왕균금%소길
肝炎,乙型%横断面研究%问卷调查
肝炎,乙型%橫斷麵研究%問捲調查
간염,을형%횡단면연구%문권조사
Hepatitis B%Cross-sectional studies%Questionnaires
目的 了解无锡市社区成人乙型肝炎(HB)知识知晓率、乙型肝炎病毒(HBV)感染率和免疫水平,探讨成人HBV免疫策略.方法 采用横断面整群抽样的方法入户问卷调查,采集空腹血样并采用ELISA方法检测HBsAg、抗-HBs、HBeAg、抗-Hbe和抗-HBc.结果 3744名调查者8项HB相关知识知晓率较高,其中"HB是传染病"单项知晓率高达87.30%,有疫苗接种史者HB知晓率得分≥5分者占60.18%(239/393),明显高于无接种史的49.49%(1071/2164),x2=17.07,P＜0.01;有HBV家族史者知晓率得分≥5分者占60.00%(318/530),明显高于无家族史者的43.00%(1382/3214),x2=53.05,P＜0.01;HBV总感染率经标化后为49.88%;HBV 5项指标全部阴性者1109名,占29.62%;HBsAg、HBeAg和抗HBc 3项同时阳性者为8例,占0.21%;HBsAg、抗-Hbe和抗-HBc 3项同时阳性者133例,占3.55%;男性抗-HBc阳性率显著高于女性,分别为59.37%和53.08%,P=0.00;HBV 5项指标阳性率随着年龄的增长而上升,20岁、80岁年龄组的HBsAg分别是为2.84%和5.69%,抗-HBs分别为44.05%和65.85%,HBeAg分别为0.64%和0.81%,抗-Hbe分别为1.93%和4.07%,抗-HBc分别为33.44%和69.11%,趋势性x2=256.16,P＜0.001;3744名调查者中有HB家族史者占14.16%(530/3744),HBV疫苗接种率为11.77%(393/3339),经标化后为20.20%,有接种疫苗史者抗-HBs阳转率为21.12%(83/393).结论 成人HBV感染率高,HBV疫苗接种率低,抗-HBs抗体水平低,提高成人HB免疫水平是降低HBV感染的重要措施.
目的 瞭解無錫市社區成人乙型肝炎(HB)知識知曉率、乙型肝炎病毒(HBV)感染率和免疫水平,探討成人HBV免疫策略.方法 採用橫斷麵整群抽樣的方法入戶問捲調查,採集空腹血樣併採用ELISA方法檢測HBsAg、抗-HBs、HBeAg、抗-Hbe和抗-HBc.結果 3744名調查者8項HB相關知識知曉率較高,其中"HB是傳染病"單項知曉率高達87.30%,有疫苗接種史者HB知曉率得分≥5分者佔60.18%(239/393),明顯高于無接種史的49.49%(1071/2164),x2=17.07,P＜0.01;有HBV傢族史者知曉率得分≥5分者佔60.00%(318/530),明顯高于無傢族史者的43.00%(1382/3214),x2=53.05,P＜0.01;HBV總感染率經標化後為49.88%;HBV 5項指標全部陰性者1109名,佔29.62%;HBsAg、HBeAg和抗HBc 3項同時暘性者為8例,佔0.21%;HBsAg、抗-Hbe和抗-HBc 3項同時暘性者133例,佔3.55%;男性抗-HBc暘性率顯著高于女性,分彆為59.37%和53.08%,P=0.00;HBV 5項指標暘性率隨著年齡的增長而上升,20歲、80歲年齡組的HBsAg分彆是為2.84%和5.69%,抗-HBs分彆為44.05%和65.85%,HBeAg分彆為0.64%和0.81%,抗-Hbe分彆為1.93%和4.07%,抗-HBc分彆為33.44%和69.11%,趨勢性x2=256.16,P＜0.001;3744名調查者中有HB傢族史者佔14.16%(530/3744),HBV疫苗接種率為11.77%(393/3339),經標化後為20.20%,有接種疫苗史者抗-HBs暘轉率為21.12%(83/393).結論 成人HBV感染率高,HBV疫苗接種率低,抗-HBs抗體水平低,提高成人HB免疫水平是降低HBV感染的重要措施.
목적 료해무석시사구성인을형간염(HB)지식지효솔、을형간염병독(HBV)감염솔화면역수평,탐토성인HBV면역책략.방법 채용횡단면정군추양적방법입호문권조사,채집공복혈양병채용ELISA방법검측HBsAg、항-HBs、HBeAg、항-Hbe화항-HBc.결과 3744명조사자8항HB상관지식지효솔교고,기중"HB시전염병"단항지효솔고체87.30%,유역묘접충사자HB지효솔득분≥5분자점60.18%(239/393),명현고우무접충사적49.49%(1071/2164),x2=17.07,P＜0.01;유HBV가족사자지효솔득분≥5분자점60.00%(318/530),명현고우무가족사자적43.00%(1382/3214),x2=53.05,P＜0.01;HBV총감염솔경표화후위49.88%;HBV 5항지표전부음성자1109명,점29.62%;HBsAg、HBeAg화항HBc 3항동시양성자위8례,점0.21%;HBsAg、항-Hbe화항-HBc 3항동시양성자133례,점3.55%;남성항-HBc양성솔현저고우녀성,분별위59.37%화53.08%,P=0.00;HBV 5항지표양성솔수착년령적증장이상승,20세、80세년령조적HBsAg분별시위2.84%화5.69%,항-HBs분별위44.05%화65.85%,HBeAg분별위0.64%화0.81%,항-Hbe분별위1.93%화4.07%,항-HBc분별위33.44%화69.11%,추세성x2=256.16,P＜0.001;3744명조사자중유HB가족사자점14.16%(530/3744),HBV역묘접충솔위11.77%(393/3339),경표화후위20.20%,유접충역묘사자항-HBs양전솔위21.12%(83/393).결론 성인HBV감염솔고,HBV역묘접충솔저,항-HBs항체수평저,제고성인HB면역수평시강저HBV감염적중요조시.
Objecgive To investigate the HB awareness,the infection rate of HBV and the immunity status among adults at the communities of Wuxi,and to provide some evidences for vaccination strategy.Methods Two communities were enrolled in the study through cluster sampling method.A household survey was conducted to collect subjects' information through a face-to-face interview and blood samples were collected to detect HBsAg,anti-HBs,HBeAg,anti-HBe and anti-HBc.Results 3744 subjects were enrolled in this study.The general knowledge coverage rate of hepatitis B was high and 87.30%respondents claimed that hepatitis B was an infectious disease.The percentage of subjects who got more than 5 scores in persons had got hepatitis B vaccination was 60.18%(239/393),and this was significantly higher than in those without vaccine inoculation(x2=17.07,P＜0.01),with the proportion being 49.49%(1071/2164).rnIe percentage of subjects who got more than 5 scores in persons had family history of HBV infection was 60.00%(318/530),and this wag significantly higher than in those without family history (x2=53.05,P＜0.01),with the proportion of 43.00%(1382/3214).The standardized HBV infection rate was 49.88%.There were 1109(29.62%)subjects whose HBsAg,anti-HBs,HBeAg,anti-HBe and HBcAg were negative.There were 8 subjects(0.21%) whose HBsAg,HBeAg and anti-HBc were positive simultaneously,and there were 133 subjects(3.55%)whose HBsAg,anti-HBe and anti-HBc were positive simultaneously.The positive rate of anti-HBc was significantly higher in males than in females( 59.37%and 53.08%,P=0.00).The positive rates of HBsAg,anti-HBs,HBeAg,anti-HBe and HBcAg were 2.84%,44.05%,0.64%,1.93%,33.44%respectively in 20 year age group,while they were 5.69%,65.85%,0.81%,4.07%,69.44%respectively in 80 year age group.The positive rates of anti-HBs,HBeAg,anti-HBe and HBcAg increased with age(x2trend=256.16,P＜0.001).Among 3744 objects,530 subjects (accounted for 14.16%)had the family history of hepatitis B.HB immunization coverage rate was 11.77% (393/3339),with the standardized rate being 20.20%.The positive conversion rate of anti-HBs among those had HB vaccine inoculation was 21.12%(83/393).Conclusion The infection rate of HBV was high,whereas the immunization rate of hepatitis B vaccine and the level of anti-HBs were low in adults,Thus,to improve the immunization rate of hepatitis B vaccine is a key step to decrease the infection rate.
