5-(1-苯基-5-甲基-1,2,3-三唑-4-基)-4-芳基-1,2,4-三唑-3-硫基乙酸的合成和抗菌活性
5-(1-분기-5-갑기-1,2,3-삼서-4-기)-4-방기-1,2,4-삼서-3-류기을산적합성화항균활성
Synthesis and Antifungal Activities of 4-Aryl-5- (1-phenyl-5-methyl-1,2,3-triazol-4-yl) -1,2,4-triazol-3-thioacetic Acids
  • 万方数据
    兰州大学学报(自然科学版) 란주대학학보(자연과학판)
    JOURNAL OF LANZHOU UNIVERSITY
    2001年 2期 91-94 ,共4页

    褚长虎%张艳%惠新平%张自义%李之春%廖仁安

    저장호%장염%혜신평%장자의%리지춘%료인안

    1,2,3-三唑%1,2,4-三唑%硫基乙酸%抗菌活性%合成 1,2,3-三唑%1,2,4-三唑%硫基乙痠%抗菌活性%閤成
    1,2,3-삼서%1,2,4-삼서%류기을산%항균활성%합성
    合成一系列新的5-(1-苯基-5-甲基-1,2,3-三唑-4-基)-4-芳基-1,2,4-三唑-3-硫基乙酸，所有化合物均经元素分析和波谱数据予以鉴定.对代表性化合物作了抗菌活性测试，结果表明它们都表现出不同程度的抗菌活性.
    합성일계렬신적5-(1-분기-5-갑기-1,2,3-삼서-4-기)-4-방기-1,2,4-삼서-3-류기을산，소유화합물균경원소분석화파보수거여이감정.대대표성화합물작료항균활성측시，결과표명타문도표현출불동정도적항균활성.
    A series of new 4-Aryl-5-(5-methyl-1-phenyl-1,2,3-triazol-4-yl)-1,2,4-triazol-3-thioacetic acids 2a-k have been synthesized by the condensation of 4-Aryl-5-(5-methyl-1-phenyl-1,2,3-triazol-3-yl)-1,2,4-triazol-3-thiones with chloroacetic acid in the presence of potassium hydroxide methanol-water solution. Supports for the structure of the synthesized compounds have been provided by their elemental analyses and spectra data. The preliminary biological test showed that the compounds possessed some antifungal activities.
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