CAJ | 학술논문

目的探讨血清C-反应蛋白(CRP)水平对慢性阻塞性肺疾病(COPD)是否出现急性加重的预测价值.方法 65例COPD患者为研究对象,用免疫透射比浊法测定其就诊次日清晨静脉血的CRP水平,患者按CRP水平分为CRP阳性组(CRP≥8 mg/L,34例)和CRP阴性组(CRP＜8 mg/L,31例),随后追踪观察两组1年内COPD急性加重例数并进行比较.结果经回顾性分析,CRP阳性组有21例,CRP阴性组有14例在1年内出现COPD急性加重.经x2检验,两组1年内出现COPD急性加重率差异无统计学意义(P＞0.05).结论用免疫透射比浊法测定就诊次日清晨静脉血的血清CRP水平对COPD患者在1年内是否出现急性加重未能见到预测价值.
목적 탐토혈청C-반응단백(CRP)수평대만성조새성폐질병(COPD)시부출현급성가중적예측개치.방법 65례COPD환자위연구대상,용면역투사비탁법측정기취진차일청신정맥혈적CRP수평,환자안CRP수평분위CRP양성조(CRP≥8 mg/L,34례)화CRP음성조(CRP＜8 mg/L,31례),수후추종관찰량조1년내COPD급성가중례수병진행비교.결과 경회고성분석,CRP양성조유21례,CRP음성조유14례재1년내출현COPD급성가중.경x2검험,량조1년내출현COPD급성가중솔차이무통계학의의(P＞0.05).결론 용면역투사비탁법측정취진차일청신정맥혈적혈청CRP수평대COPD환자재1년내시부출현급성가중미능견도예측개치.
Objective To assess the effectiveness of serum C-reactive protein(CRP)in the prognosis of the acute exacerbation of chronic obstructive pulmonary disease(COPD).Methods Sixty-five patients with COPD were taken as study subjects.Their serum CRP concentration was measured on the second day of hospitalization.According to the CRP levels measured,the study subjects were divided into two groups,CRP positive group(CRP≥8 mg/L,34 cases)and CRP negative group(CRP＜8 mg/L,31 cases).In the subsequent one year,the two groups were observed and compared in terms of the instances of the acute exacerbation of COPD.Results According tO the retrospective observation,in the duration of one year,there were 21 cases of acute exacerbation of COPD in CRP positive group and 14 cases in CRP negative group.The difference in acute exacerbation between two groups is insignificant(P＞0.05).Conclusions The initial measurement of serum CRP concentration in the COPD patients by the immunity-turbidity method(on the second day of hospitalization)has proven to be ineffective in the prognosis for acute exacerbation of COPD in one year.