CAJ | 학술논문

目的探讨高压氧早期治疗弥漫性轴索损伤(diffuse axonal injury,DAI)的疗效和机制. 方法 45例DAI患者随机分为常规治疗组20例和高压氧治疗组25例,观察治疗前后颅内压以及GCS评分平均值的变化和预后情况. 结果高压氧治疗组较常规治疗组早期颅内压值明显降低,GCS评分平均值曲线抬高,预后良好率明显提高.两者比较差异有统计学意义(P＜0.05).结论早期高压氧辅助治疗DAI患者,可以明显降低患者颅内压,改善其预后.
목적 탐토고압양조기치료미만성축색손상(diffuse axonal injury,DAI)적료효화궤제. 방법 45례DAI환자수궤분위상규치료조20례화고압양치료조25례,관찰치료전후로내압이급GCS평분평균치적변화화예후정황. 결과 고압양치료조교상규치료조조기로내압치명현강저,GCS평분평균치곡선태고,예후량호솔명현제고.량자비교차이유통계학의의(P＜0.05).결론 조기고압양보조치료DAI환자,가이명현강저환자로내압,개선기예후.
Objective To explore the effect and mechanism of early hyperbaric oxygen in the treatment of patients with diffuse axonal injury ( DAI ). Methods A total of 45 cases of DAI were randomly divided into hyperbaric oxygen treatment group ( n =25 ) and normal treatment group ( n =20).The changes of intracranial pressure,Glasgow Comb Scale (GCS) and prognosis were observed.Results Compared with group treated with routine therapy,early intracranial pressure scores were reduced obviously,while GCS and prognosis were increased obviously in group treated with hyperbaric oxygen therapy ( P ＜ 0.05 ). Conclusion Early hyperbaric oxygen can significantly lower the level of intracranial pressure and improve the prognosis in the treatment of DAI patients.