CAJ | 학술논문

背景:国内人群超声骨密度正常值及其标准差尚未建立. 目的:了解深圳地区6～12岁少年超声骨密度状况;建立该年龄段少年超声骨密度正常参考值. 设计:横断面调查. 单位:深圳市龙岗区人民医院超声科. 对象:选择2002-03/2003-04深圳市一所幼儿园,一所小学,一所中学自愿进行超声骨密度测定者.排除各种可能影响骨代谢的主要疾病、曾发生骨折者和6个月内服用激素等影响骨代谢药物,女性无月经史.筛选出正常儿童697例,男367例,女330例;6～12岁. 方法:采用美国SAHARA超声骨密度仪,开机后用标准体模校正,精确性误差＜1%,准确性误差为3%.测定受试者左足跟骨密度,用同一身高、体重计,测量受检者的体质量和身高. 主要观察指标:6～12岁儿童足跟部骨密度与性别、年龄和体质量的相关性. 结果:6～12岁儿童骨密度正常参考值分别为:6岁(0.445±0.166)g/cm2,7岁(0509±0.151)c,8岁(0.510±0.133)g/cm2,9岁(0.519±0.132)g/cm2,10岁(0.520±0.153)g/cm2,11岁(0.530±0.175)g/cm2,12岁(0.545±0.206)g/cm2.男童与女童骨密度之间存在差别(P＜0.001),经体质量较正后,差别消失.男童与女童骨密度随年龄增加呈线性增长(男童r=0.722,P＜0.001;女童r=0.785,P＜0.001),并与体质量显著相关(r=0.984,P＜0.001). 结论:6～12岁儿童足跟部骨密度与性别无关,而与年龄增加呈线性增长,这种增长与体质量显著相关.
배경:국내인군초성골밀도정상치급기표준차상미건립. 목적:료해심수지구6～12세소년초성골밀도상황;건립해년령단소년초성골밀도정상삼고치. 설계:횡단면조사. 단위:심수시룡강구인민의원초성과. 대상:선택2002-03/2003-04심수시일소유인완,일소소학,일소중학자원진행초성골밀도측정자.배제각충가능영향골대사적주요질병、증발생골절자화6개월내복용격소등영향골대사약물,녀성무월경사.사선출정상인동697례,남367례,녀330례;6～12세. 방법:채용미국SAHARA초성골밀도의,개궤후용표준체모교정,정학성오차＜1%,준학성오차위3%.측정수시자좌족근골밀도,용동일신고、체중계,측량수검자적체질량화신고. 주요관찰지표:6～12세인동족근부골밀도여성별、년령화체질량적상관성. 결과:6～12세인동골밀도정상삼고치분별위:6세(0.445±0.166)g/cm2,7세(0509±0.151)c,8세(0.510±0.133)g/cm2,9세(0.519±0.132)g/cm2,10세(0.520±0.153)g/cm2,11세(0.530±0.175)g/cm2,12세(0.545±0.206)g/cm2.남동여녀동골밀도지간존재차별(P＜0.001),경체질량교정후,차별소실.남동여녀동골밀도수년령증가정선성증장(남동r=0.722,P＜0.001;녀동r=0.785,P＜0.001),병여체질량현저상관(r=0.984,P＜0.001). 결론:6～12세인동족근부골밀도여성별무관,이여년령증가정선성증장,저충증장여체질량현저상관.
BACKGROUND: The normal clinical index and the standard error of ultrasonic bone density in the population of normalchildren aged 6-12 years have not yet been established. OBJECTIVE: To investigate the status of ultrasonic bone density in the population of normal children aged 6 to 12 years old in Shenzhen City and establish a normal reference index of ultrasonic bone density of this population. DESIGN: Cross-sectional survey. SETTING: Ultrasound Department of People's Hospital in Longgang District of Shenzhen City. PARTICIPANTS: The volunteers for ultrasonic bone density detection were chosen froma kindergarten, an elementary school and a middle school between March 2002 and April2003. Excluded were those who had bone fracture and received medication of hormone and other drugs within 6months that affected bone metabolism, and menstrual history. Altogether we chose 697 normal children, 367 boys and 330 girls whose age ranged from 6 to 12 years old. METHODS: SAHARA ultrasonic bone density apparatus (the US) was used, and corrected according to the standard body model after the operation began.The error of precision was below 1％ and the error of accuracy was 3％. Bone density of the left heel of the children was detected and body mass (kg) and height (cm) were also measured using the same height and weight scale. MAIN OUTCOME MEASURES: The correlation between bone densityof the heel and sex, age and body mass in the population of normal children aged 6 to 12 years. RESULTS: The normal reference values of bone density in the population from 6 to 12 years old were (0.445±0.166) g/cm2 in 6-year-old group,(0.509±0.151) g/cm2 in 7-year-old group, (0.510±0.133) g/cm2 in 8-year-old group, (0.519±0.132) g/cm2 in 9-year-old group, (0.520±0.153) g/cm2 in 10-year-old group, (0.53 ±0.175) g/cm2 in 11-year-old, and (0.545±0.206) g/cm2 in 12-year-old group. There were differences in bone density between boys and girls (P ＜ 0.001), and after correction by body mass, the difference disappeared. Bone density of the boys and girls had increasing linear correlation with age (male r=0.722, P ＜ 0.001; female r=0.785, P ＜ 0.001), and had significant relationship with body mass (r=0.984, P ＜ 0.001). CONCLUSION: In normal children aged 6 to 12 years old, bone density of the heel has no association with sex, but has increasing linear correlation with age and significant relationship with body mass.