CAJ | 학술논문

目的探讨内囊警示综合征(capsular warning syndrome,CWS)的临床特征和影像学表现.方法对2008年11月至2009年12月11例连续住院CWS患者的临床和影像学资料进行回顾性分析.结果 11例CWS患者中,5例患者表现为单纯运动症状,4例患者表现为单纯感觉症状,2例患者表现为运动和感觉同时受累症状.10例患者接受了头颅及颈部磁共振血管造影检查,结果未发现有明显的大动脉狭窄.11例CWS患者中最后有7例发展为脑卒中,所有脑卒中病灶都位于内囊.所有的CWS患者都有脑卒中的危险因素;其中,6例是吸烟者,7例有高血压病史,5例有高血脂,1例有糖尿病史,1例既往有脑卒中病史.所有患者随访(10.2±3.4)个月后的修正Rankin评分为0.73±1.20.结论 CWS与大动脉狭窄无明显关联,而可能是一种脑的深部小动脉疾病.
목적 탐토내낭경시종합정(capsular warning syndrome,CWS)적림상특정화영상학표현.방법 대2008년11월지2009년12월11례련속주원CWS환자적림상화영상학자료진행회고성분석.결과 11례CWS환자중,5례환자표현위단순운동증상,4례환자표현위단순감각증상,2례환자표현위운동화감각동시수루증상.10례환자접수료두로급경부자공진혈관조영검사,결과미발현유명현적대동맥협착.11례CWS환자중최후유7례발전위뇌졸중,소유뇌졸중병조도위우내낭.소유적CWS환자도유뇌졸중적위험인소;기중,6례시흡연자,7례유고혈압병사,5례유고혈지,1례유당뇨병사,1례기왕유뇌졸중병사.소유환자수방(10.2±3.4)개월후적수정Rankin평분위0.73±1.20.결론 CWS여대동맥협착무명현관련,이가능시일충뇌적심부소동맥질병.
Objective To evaluate the relationship between stenosis of intra- or extra-cranial cerebral large artery and capsular warning syndrome(CWS). Methods Eleven consecutive CWS patients hospitalized during period of time from November 2008 to December 2009 were retrospectively analyzed.Result In these 11 patients with CWS, 5 patients had motor symptoms only, 4 patients had pure sensory symptoms, and 2 patients had sensorimotor symptoms. Ten patients underwent cervical contrast-enhanced MRA and intracranial MRA examination. The results showed no sign of arterial stenosis. Seven CWS patients eventually had strokes, 1 progressed to stroke despite receiving the therapy of antiplatelet and anticoagulation. All stroke lesions were located in the capsula interna. All the CWS patients had vascular risks: 7 were smoker, 8 had hypertension, 1 had diabetes mellitus, and 5 had hyperlipidemia. One patient had a history of previous stroke; no patient had a history of ischemic heart disease or atrial fibrillation. At follow-up(10. 2 ±3.4)mouths, the average modified Rankin scale score for all patients was 0. 73 ± 1.20.Conclusion CWS was not associated with stenosis of the intra and extra-cranial large cerebral arteries.CWS may be associated with small-vessel single-penetrator disease.