CAJ | 학술논문

目的探讨原发性胆囊癌的不同治疗方式、不同病理分期及分化程度对预后的影响.方法对1994年12月至2003年12月间连续收治的96例原发性胆囊癌病例的临床病理特点、不同的治疗方式及其随访结果进行生存分析. 结果 96例中手术治疗61例,非手术治疗及放弃治疗者35例.获得随访77例(80%).Nevin Ⅰ～Ⅲ期患者的预后明显好于NevinⅣ～Ⅴ期患者.R0及R1切除术的3年生存率分别为80%及20%,R2切除术患者平均生存期为5.2个月,未行切除的患者平均生存期为2.5个月. 结论早期诊断、R0手术是胆囊癌患者长期存活的关键,病理分期对胆囊癌的预后有重要影响.
목적 탐토원발성담낭암적불동치료방식、불동병리분기급분화정도대예후적영향.방법 대1994년12월지2003년12월간련속수치적96례원발성담낭암병례적림상병리특점、불동적치료방식급기수방결과진행생존분석. 결과 96례중수술치료61례,비수술치료급방기치료자35례.획득수방77례(80%).Nevin Ⅰ～Ⅲ기환자적예후명현호우NevinⅣ～Ⅴ기환자.R0급R1절제술적3년생존솔분별위80%급20%,R2절제술환자평균생존기위5.2개월,미행절제적환자평균생존기위2.5개월. 결론조기진단、R0수술시담낭암환자장기존활적관건,병리분기대담낭암적예후유중요영향.
Objective To evaluate the operative modality,pathological grade and tumor differentiation of patients with primary carcinoma of the gallbladder in their relations with prognosis.Methods The clinical and follow-up data of 96 consecutive patients with primary carcinoma of the gallbladder were retrospectively analyzed.Results Seventy-seven cases were followed-up.Patients treated by R0 resection had a 3 year survival rate of 80%,while it was only 20%for R1 resection group.Patients with R2 resection had an average survival of 5.2 months,96%patients that treated conservatively died within the first 6 month with a mean survival time of 2.5 months. Conclusions The postoperative prognosis is mainly determined by the pathological stage of the tumor and the surgical margins.Early diagnosis and R0 resection are essential for a long survival time for patients with gallbladder carcinoma.