CAJ | 학술논문

目的探讨高致病性禽流感A/H5N1病毒感染(简称人禽流感)患者的临床特点及治疗经验.方法总结2009年1月中南大学湘雅医院成功救治的1例确诊的人禽流感患者的临床表现、实验室检查、影像学改变和诊治过程中的成功经验.结果患者经逆转录-聚合酶链反应(RT-PCR)方法确诊为人禽流感病例.患者女,21岁.以发热、咳嗽、呼吸困难为主要症状,肺部病灶进展快,并伴有多器官功能障碍.经早期奥司他韦抗病毒治疗及加强器官功能维护,患者康复出院.结论早发现、早诊断、早期合理使用抗病毒治疗,积极维护脏器功能,防治多器官功能衰竭可挽救患者的生命.
목적 탐토고치병성금류감A/H5N1병독감염(간칭인금류감)환자적림상특점급치료경험.방법 총결2009년1월중남대학상아의원성공구치적1례학진적인금류감환자적림상표현、실험실검사、영상학개변화진치과정중적성공경험.결과 환자경역전록-취합매련반응(RT-PCR)방법학진위인금류감병례.환자녀,21세.이발열、해수、호흡곤난위주요증상,폐부병조진전쾌,병반유다기관공능장애.경조기오사타위항병독치료급가강기관공능유호,환자강복출원.결론 조발현、조진단、조기합리사용항병독치료,적겁유호장기공능,방치다기관공능쇠갈가만구환자적생명.
Objective To study the clinical features and successful management of a survived human case with A/H5N1infection.Methods The data of a confirmed case of human case with A/H5N1 infection in Hunan province were collected and analyzed.Results This patient with A/H5N1 infection inHunan province was confirmed by reverse-transcription polymerase chain reaction (RT-PCR) for A/H5N1in airway secretions.The main clinical presentations included fever,cough and dyspnea.An extensive pulmonary infiltration developed quickly,followed by multi-organ dysfunction.Early administration of osehamivir,early protection of organ function and extensive support were effective for the cure of the disease in this case.Conclusion Early administration of oseltamivir,early protection of organ function and adequate support therapy may be useful for the treatment of human A/H5N1infection.