中华麻醉学杂志
中華痳醉學雜誌
중화마취학잡지
CHINESE JOURNAL OF ANESTHESIOLOGY
2011年
2期
166-167
,共2页
右美托咪啶%儿童%麻醉恢复期%躁动%七氟醚
右美託咪啶%兒童%痳醉恢複期%躁動%七氟醚
우미탁미정%인동%마취회복기%조동%칠불미
Dxmedetomidine%Child%Anesthesia recovery period%Psychomotor agitation%Sevoflurane
目的 评价右美托咪啶对七氟醚麻醉患儿麻醉恢复期躁动的影响.方法 择期全麻下行耳鼻喉科手术患儿300例,ASA分级Ⅰ或Ⅱ级,性别不限,年龄4～7岁,体重16～30 kg,采用随机数字表法,将其随机分为2组(n=150):对照组(C组)和右美托咪啶组(D组).D组麻醉诱导前经10min静脉输注0.5μg/kg右美托咪啶20 ml,C组输注生理盐水20 ml.给药结束后5 min时吸入8%七氟醚麻醉诱导,气管插管后行机械通气.吸人2%～ 3%七氟醚维持麻醉,术中维持BIS值40～60.记录麻醉恢复时间和术后2 h内躁动的发生情况.结果 与C组比较,D组麻醉恢复时间差异无统计学意义(P>0.05),躁动发生率降低(P<0.05).结论 右美托咪啶可降低七氟醚麻醉患儿麻醉恢复期躁动的发生.
目的 評價右美託咪啶對七氟醚痳醉患兒痳醉恢複期躁動的影響.方法 擇期全痳下行耳鼻喉科手術患兒300例,ASA分級Ⅰ或Ⅱ級,性彆不限,年齡4～7歲,體重16～30 kg,採用隨機數字錶法,將其隨機分為2組(n=150):對照組(C組)和右美託咪啶組(D組).D組痳醉誘導前經10min靜脈輸註0.5μg/kg右美託咪啶20 ml,C組輸註生理鹽水20 ml.給藥結束後5 min時吸入8%七氟醚痳醉誘導,氣管插管後行機械通氣.吸人2%～ 3%七氟醚維持痳醉,術中維持BIS值40～60.記錄痳醉恢複時間和術後2 h內躁動的髮生情況.結果 與C組比較,D組痳醉恢複時間差異無統計學意義(P>0.05),躁動髮生率降低(P<0.05).結論 右美託咪啶可降低七氟醚痳醉患兒痳醉恢複期躁動的髮生.
목적 평개우미탁미정대칠불미마취환인마취회복기조동적영향.방법 택기전마하행이비후과수술환인300례,ASA분급Ⅰ혹Ⅱ급,성별불한,년령4～7세,체중16～30 kg,채용수궤수자표법,장기수궤분위2조(n=150):대조조(C조)화우미탁미정조(D조).D조마취유도전경10min정맥수주0.5μg/kg우미탁미정20 ml,C조수주생리염수20 ml.급약결속후5 min시흡입8%칠불미마취유도,기관삽관후행궤계통기.흡인2%～ 3%칠불미유지마취,술중유지BIS치40～60.기록마취회복시간화술후2 h내조동적발생정황.결과 여C조비교,D조마취회복시간차이무통계학의의(P>0.05),조동발생솔강저(P<0.05).결론 우미탁미정가강저칠불미마취환인마취회복기조동적발생.
Objective To investigate the effect of dexmedetomidine on agitation during recovery from sevoflurane anesthesia in children. Methods Three hundred ASA Ⅰ or Ⅱ children, aged 4-7 yr, weighing 16-30kg, scheduled for elective ear-nose-throat operation under general anesthesia, were randomly divided into 2 groups ( n = 150 each) : control group (group C) and dexmedetomidine group (group D) . Dexmedetomidine 0.5 μg/kg in 20 ml was infused intravenously over 10 min before anesthesia induction in group D, while equal volume of normal Saline was infused in group C. Anesthesia was induced with inhalation of 8 % sevoflurane 5 min after the end of administration . The children were tracheal incubated and mechanically ventilated. Anesthesia was maintained with inhalation of 2 % -3 % sevoflurane. BIS was maintained at 40-60 during operation. The recovery time and agitation within 2 h after operation were recorded. Results There was no significant difference in the recovery time between the two groups ( P > 0.05) . The incidence of agitation was significantly lower in group D than in group C ( P <0.05 ) . Conclusion Dexmedetomidine can reduce the occurrence of agitation during recovery from sevoflurane anesthesia in children.
