CAJ | 학술논문

目的分析视神经脊髓炎(neuromyelitis optica,NMO)患者头颅MRI特点.方法对27例NMO患者的头颅MRI进行回顾性分析.结果 22例(81.5%)NMO患者存在不同类型的头部病灶,并可分为非特异性(7例)、非典型性(1例)、多发性硬化样(MS-like,3例)及脑室-导水管-中央管周围型(11例),但以脑室-导水管-中央管周围型最为常见(40.7%),且NMO患者颅内的病灶数与最后一次MRI检查的时间呈正相关(r=0.475,P=0.025).结论 NMO患者脑内病灶类型多样,但以脑室-导水管-中央管周围型最为常见,可能存在不同机制.对疑似病例早期进行头颅MRI检查相当必要.
목적 분석시신경척수염(neuromyelitis optica,NMO)환자두로MRI특점.방법 대27례NMO환자적두로MRI진행회고성분석.결과 22례(81.5%)NMO환자존재불동류형적두부병조,병가분위비특이성(7례)、비전형성(1례)、다발성경화양(MS-like,3례)급뇌실-도수관-중앙관주위형(11례),단이뇌실-도수관-중앙관주위형최위상견(40.7%),차NMO환자로내적병조수여최후일차MRI검사적시간정정상관(r=0.475,P=0.025).결론 NMO환자뇌내병조류형다양,단이뇌실-도수관-중앙관주위형최위상견,가능존재불동궤제.대의사병례조기진행두로MRI검사상당필요.
Objective To investigate the changes in brain MRI scan in neuromyelitis optica (NMO).Methods MRI images in 27 cases with NMO were examined in a retrospective study.Results Twenty-two of 27 patients (81.5%) had abnormal brain MRI findings,which were classified as nonspecific (7 cases),atypical (1 case),multiple sclerosis-like (3 cases) and ventricle-aqueduct-syringocoele lesions (11 cases).The lust type is the most common (40.7%).Furthermore,the analysis showed that the number of brain lesions positively correlated with lag time from the onset to the last MRI scan (r=0.475,P=0.025).Conclusions Brain lesions in NMO are diverse,which might result from different pathogenesis.However,ventricle-aqueduct-syringocoele is the most common lesion.Early brain MRI examination of suspected cases is essential.