中国民族民间医药
中國民族民間醫藥
중국민족민간의약
CHINESE JOURNAL OF ETHNOMEDICINE AND ETHNOPHARMACY
2009年
14期
28-29
,共2页
大肠埃希菌%超广谱β-内酰胺酶%耐药性%氟喹诺酮类
大腸埃希菌%超廣譜β-內酰胺酶%耐藥性%氟喹諾酮類
대장애희균%초엄보β-내선알매%내약성%불규낙동류
E .coli%ESBLs%resistance%fluquinolone
目的:分析我院产超广谱β-内酰胺酶大肠埃希菌对氟喹诺酮类的耐药性.为临床合理应用氟喹诺酮类抗菌药物提供实验室依据.方法:对2007年11月～2008年11月我院临床分离的118株产ESBLs大肠埃希菌,用MIC琼脂稀释法做药物敏感试验,分析产ESBLs大肠埃希菌对临床常用氟喹诺酮类的耐药性.结果:118株大肠埃希菌中,107株对环丙沙星耐药,93株对左氧氟沙星耐药,106株对莫西沙星耐药,耐药率分别为90.67%、78.81%、89.83%.结论:我院临床分离大肠埃希菌对氟喳诺酮类抗菌药物耐药十分严重,在临床抗感染治疗时,应调整氟喹诺酮类抗菌药物的使用频率,以减少其耐药性的产生.
目的:分析我院產超廣譜β-內酰胺酶大腸埃希菌對氟喹諾酮類的耐藥性.為臨床閤理應用氟喹諾酮類抗菌藥物提供實驗室依據.方法:對2007年11月～2008年11月我院臨床分離的118株產ESBLs大腸埃希菌,用MIC瓊脂稀釋法做藥物敏感試驗,分析產ESBLs大腸埃希菌對臨床常用氟喹諾酮類的耐藥性.結果:118株大腸埃希菌中,107株對環丙沙星耐藥,93株對左氧氟沙星耐藥,106株對莫西沙星耐藥,耐藥率分彆為90.67%、78.81%、89.83%.結論:我院臨床分離大腸埃希菌對氟喳諾酮類抗菌藥物耐藥十分嚴重,在臨床抗感染治療時,應調整氟喹諾酮類抗菌藥物的使用頻率,以減少其耐藥性的產生.
목적:분석아원산초엄보β-내선알매대장애희균대불규낙동류적내약성.위림상합리응용불규낙동류항균약물제공실험실의거.방법:대2007년11월～2008년11월아원림상분리적118주산ESBLs대장애희균,용MIC경지희석법주약물민감시험,분석산ESBLs대장애희균대림상상용불규낙동류적내약성.결과:118주대장애희균중,107주대배병사성내약,93주대좌양불사성내약,106주대막서사성내약,내약솔분별위90.67%、78.81%、89.83%.결론:아원림상분리대장애희균대불사낙동류항균약물내약십분엄중,재림상항감염치료시,응조정불규낙동류항균약물적사용빈솔,이감소기내약성적산생.
objective:To celarify the fluquinolones-resistance in Escherichia coli(E.coli) clinical isolated from our hospital and to provide doctors with clinical evidence.Methods: The isolates ESBLs-Produeing E .coli from 2007.11 to 2008.11 in the hospital were colleeted. The MICs of fluquinolones were detceted by argrose dilution.Results:There are 107(90.67%) islates of 118 E.colis resisted to ciprofloxacin,93(78.81%)were resistan to levofloxacin,and 106(89.83%) were resistant to moxifloxacin. Conclusion:the fluquinolone-resistance among the clinical isolates of E.coli in the hospital was critical.it is necessary that avoiding the extensively use this agents in order to control the fluquinolones- resistance.
