软珊瑚Nephthea sp.中新生物碱分离与结构鉴定
연산호Nephthea sp.중신생물감분리여결구감정
A New Alkaloid from the Soft Coral Nephthea sp.
  • 万方数据
    天然产物研究与开发 천연산물연구여개발
    NATURAL PRODUCT RESEARCH AND DEVELOPMENT
    2010年 1期 1-4 ,共4页

    王长军%徐石海%廖小建%林慧

    왕장군%서석해%료소건%림혜

    软珊瑚%生物碱%结构鉴定 軟珊瑚%生物堿%結構鑒定
    연산호%생물감%결구감정
    soft coral%alkaloid%nephoxaloid%cytotoxic activities
    一个新的化合物Nephoxaloid(1)具有独特的三环骨架结构和一个已知的化合物蕨藻素Caulerpin(2)从中国国西沙群岛的软珊瑚Nephthea sp.中分离得到.通过NMR和Ms对它们的平面结构进行分析,化合物(1)和(2)对少数癌细胞株具有细胞毒性作用也有报道.
    일개신적화합물Nephoxaloid(1)구유독특적삼배골가결구화일개이지적화합물궐조소Caulerpin(2)종중국국서사군도적연산호Nephthea sp.중분리득도.통과NMR화Ms대타문적평면결구진행분석,화합물(1)화(2)대소수암세포주구유세포독성작용야유보도.
    Nephoxaloid (1), possessing an unprecedented tricyclo-skeleton, together with the known alkaloid Caulerpin (2) have been isolated from the soft coral Nephthea sp.Collected in the Xisha island of China.Their planar structures were established by NMR and MS spectroscopic analysis.The cytctoxic activity of them toward a limited panel of cancer cell lines is also reported.
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