CAJ | 학술논문

目的研究在不同愈合时间和负载条件下微型种植体支抗-骨界面压力侧和非压力侧的组织学变化.方法选用纯种Beagle犬8只,在其上颌根间牙槽骨中植入86颗微型种植体支抗,分别进行即刻负载、愈合2周、愈合4周、愈合12周后加载150 g和300 g牵引力,定期注射荧光标志物,加载2个月后处死动物.标记种植体的压力侧和非压力侧,两侧分别进行种植体颈部骨结合率(BIC)、骨充填率(BSA)和矿物沉积率(MAR)的测量以及HE染色组织形态观察,以BIC和BSA作为骨整合能力的观察指标.结果即刻负载组和愈合2周负载300克组压力侧的骨整合能力、矿物沉积率和骨改建活跃程度均小于非压力侧,其余各组则相反.不同负载力值组间比较无显著性差异.结论微型种植体支抗-骨界面颈部即刻负载时压力侧的骨整合和骨改建较非压力侧低,随着愈合时间的延长,压力侧相对增强,非压力侧相对降低,而负载力值对界面的影响较小.
목적 연구재불동유합시간화부재조건하미형충식체지항-골계면압력측화비압력측적조직학변화.방법 선용순충Beagle견8지,재기상합근간아조골중식입86과미형충식체지항,분별진행즉각부재、유합2주、유합4주、유합12주후가재150 g화300 g견인력,정기주사형광표지물,가재2개월후처사동물.표기충식체적압력측화비압력측,량측분별진행충식체경부골결합솔(BIC)、골충전솔(BSA)화광물침적솔(MAR)적측량이급HE염색조직형태관찰,이BIC화BSA작위골정합능력적관찰지표.결과 즉각부재조화유합2주부재300극조압력측적골정합능력、광물침적솔화골개건활약정도균소우비압력측,기여각조칙상반.불동부재력치조간비교무현저성차이.결론 미형충식체지항-골계면경부즉각부재시압력측적골정합화골개건교비압력측저,수착유합시간적연장,압력측상대증강,비압력측상대강저,이부재력치대계면적영향교소.
Objective To investigate the histological difference at the bone-implant interface between pressure and non-pressure sides of the mini-screw implant anchorage (MIA) under the condition of different loading force and heeling time. Methods Eighty-six MIAs were inserted in the maxillary alveolar bone between the dental roots in 8 beagles. Healing after 0, 2, 4, 12 weeks, 150 g and 300 g forces were loaded perpendicularly to the implants and fluorochrome was injected. Two months later, all dogs were sacrificed. The slices of MIA on the pressure and non-pressure sides were labeled. Bone implant contact ratio(BIC), bone surface area(BSA) and mineral apposition rate (MAR) were measured and histological observations were carried out. Results BIC, BSA, MAR and bone remodeling on the pressure side were lower than those on the non-pressure side in the immediate loading group and the group healing after 2 weeks with 300 g force, while the reverse result was observed in the rest of the groups. No significant difference was found between the two different force loading groups. Conclusions Bone integration and remodeling on the pressure side of MIA-bone interface was lower than those on the non-pressure side in the immediate loading group. With the healing time, it was relatively increased on the pressure side while decreased on the non-pressure side.