CAJ | 학술논문

目的探讨血尿酸(UA)水平对冠状动脉慢血流现象(CSFP)的影响。方法选取30例CSFP患者为冠脉慢血流组，30例冠脉有病变者为冠心病(CHD)组，30例冠脉造影检查正常者为健康对照组，分别测量三组血UA水平。对冠脉慢血流组及健康对照组分别测定左前降支、回旋支和右侧冠状动脉TIMI帧计数(TFC)值，并分析冠脉慢血流组患者平均TFC值与血UA之间的关系。结果冠状动脉慢血流组与健康对照组比较，左前降支、回旋支以及右侧冠状动脉TFC值均显着高于对照组（均P＜0.05）；冠状动脉慢血流组血UA水平为（340.79±79.40）μmol/L，对照组UA水平为(220.45±82.34) μmol/L，CHD组UA水平为(426.25±87.02)μmol/L，差异有统计学意义（均P＜0.05）。冠状动脉慢血流组血UA水平与冠状动脉TFC值呈正相关(r =0.943，P=0.007)。结论血UA水平的升高与CSFP的发生与发展密切相关。
목적 탐토혈뇨산(UA)수평대관상동맥만혈류현상(CSFP)적영향。방법 선취30례CSFP환자위관맥만혈류조，30례관맥유병변자위관심병(CHD)조，30례관맥조영검사정상자위건강대조조，분별측량삼조혈UA수평。대관맥만혈류조급건강대조조분별측정좌전강지、회선지화우측관상동맥TIMI정계수(TFC)치，병분석관맥만혈류조환자평균TFC치여혈UA지간적관계。결과 관상동맥만혈류조여건강대조조비교，좌전강지、회선지이급우측관상동맥TFC치균현착고우대조조（균P＜0.05）；관상동맥만혈류조혈UA수평위（340.79±79.40）μmol/L，대조조UA수평위(220.45±82.34) μmol/L，CHD조UA수평위(426.25±87.02)μmol/L，차이유통계학의의（균P＜0.05）。관상동맥만혈류조혈UA수평여관상동맥TFC치정정상관(r =0.943，P=0.007)。결론 혈UA수평적승고여CSFP적발생여발전밀절상관。
Objective To investigate on the impact of the serum uric acid (UA) level coronary slow flow phenomenon(CSFP).Methods Selected 30 cases of coronary slow flow patients as CSFP group,30 cases of patients with coronary heart disease,30 cases of patients with angiographically normal as the control group.The serum UA level was measured in three groups.The CSFP group and the control group were measured left anterior descending,circumflex and right coronary artery TIMI frame count(TFC) value.To analyze the mean TFC value of CSFP patients and the relationship between the serum UA level.Results Compared with the control group,the left anterior descending,circumflex and right coronary TFC results were significantly higher(all P ＜ 0.05) in the CSFP group.The mean serum UA level of CSFP group ,control group and CHD group were(340.79 ± 79.40)μmol/L, (220.45 ± 82.34)μmol/L,(42625 ± 87.02) μmol/L, the difference was statistically significant (all P ＜ 0.05).The mean serum UA level and TFC value of CSFP group was positively correlated(r = 0.943, P = 0.007).Conclusion Elevated level of serum UA is closely related to the occurrence and development of the CSFP.