CAJ | 학술논문

目的探讨皮炎湿疹类皮肤病接触性致敏原及其特点,以期更好地诊断与治疗.方法对340例皮炎湿疹类皮肤病患者采用标准筛选抗原进行斑贴试验.结果 340例患者中275例对20种标准筛选抗原中的18种出现1种或1种以上抗原阳性反应,总阳性反应率为80.88%,其中以硫酸镍阳性率最高,达29.70%,其余阳性率较高者依次为重铬酸钾(27.64%)、芳香混合物(22.35%)、卡巴混合物(20.29%)、硫柳汞(18.82%.)、苯唑卡因(17.94%).结论硫酸镍、重铬酸钾、芳香混合物、卡巴混合物是目前引起皮炎湿疹类患者的主要变应原,斑贴试验有助于明确皮炎湿疹类变态反应性皮肤病及接触性致敏原及其性质.
목적 탐토피염습진류피부병접촉성치민원급기특점,이기경호지진단여치료.방법 대340례피염습진류피부병환자채용표준사선항원진행반첩시험.결과 340례환자중275례대20충표준사선항원중적18충출현1충혹1충이상항원양성반응,총양성반응솔위80.88%,기중이류산얼양성솔최고,체29.70%,기여양성솔교고자의차위중락산갑(27.64%)、방향혼합물(22.35%)、잡파혼합물(20.29%)、류류홍(18.82%.)、분서잡인(17.94%).결론 류산얼、중락산갑、방향혼합물、잡파혼합물시목전인기피염습진류환자적주요변응원,반첩시험유조우명학피염습진류변태반응성피부병급접촉성치민원급기성질.
Objective To investigate the characteristics of contact allergens in eczema and dermatitis for further diagnosis and treatment. Methods 340 cases with eczema and dermatitis were tested with a standardized screening antigen kit. Results (80. 88% ) of the 340 patients tested had at least one positive allergen among 18 of 20 standardized screening antigen. The first six allergens were nickel sulfate ( 29. 70% ), potassium dichroroate (27.64% ) ,fragrant mix(22.35% ) ,carba mix(20.29% ) ,thimerosal( 18. 82% ) ,benzocaine( 17.94% ). Conclusion Nickel sulfate,potassium dichromate,fragrance mix and carba mix were the main allergens causing dermatitis and eczema presently. Patch-testing was helpful in identifying the property of contact allergens in para eczema and dermatitis.