中国基层医药
中國基層醫藥
중국기층의약
CHINESE JOURNAL OF PRIMARY MEDICINE AND PHARMACY
2009年
12期
2155-2156
,共2页
还原型谷胱甘肽%丹参%脂肪肝%血脂
還原型穀胱甘肽%丹參%脂肪肝%血脂
환원형곡광감태%단삼%지방간%혈지
Reduced Glutathione%Danshen Root%Fatty liver%Lipids
目的 探讨还原型谷胱甘肽联合丹参治疗脂肪肝的疗效及CT扫描在疗效观察中的定量作用.方法 对38例脂肪肝病人进行还原型谷胱甘肽联合丹参治疗,观察治疗前后肝功、血脂及肝脏CT值的变化情况.结果 治疗后谷丙转氨酶(ALT)由原来(205.4±9.7)U/L下降为(87.4±5.3)U/L,总胆固醇(TC)从(7.8±1.3)mmol/L下降为(4.2±1.0)mmol/L,甘油三酯(TG)由(2.7±0.3)mmol/L降为(1.6±0.3)mmol/L,肝脏CT值由原来(26±8)Hu,增高至(37±11)Hu,治疗前后对比有统计学意义(P＜0.01),还原型谷胱甘肽联合丹参组较单独使用丹参组各项指标改变更明显,两组差异有统计学意义(P＜0.01).结论 还原型谷胱甘肽联合丹参箔疗脂肪肝效果良好,值得临床中广泛推广使用,利用肝脏CT值这一指标观察药物疗效目前尚处于初步探讨阶段,值得进一步研究.
目的 探討還原型穀胱甘肽聯閤丹參治療脂肪肝的療效及CT掃描在療效觀察中的定量作用.方法 對38例脂肪肝病人進行還原型穀胱甘肽聯閤丹參治療,觀察治療前後肝功、血脂及肝髒CT值的變化情況.結果 治療後穀丙轉氨酶(ALT)由原來(205.4±9.7)U/L下降為(87.4±5.3)U/L,總膽固醇(TC)從(7.8±1.3)mmol/L下降為(4.2±1.0)mmol/L,甘油三酯(TG)由(2.7±0.3)mmol/L降為(1.6±0.3)mmol/L,肝髒CT值由原來(26±8)Hu,增高至(37±11)Hu,治療前後對比有統計學意義(P＜0.01),還原型穀胱甘肽聯閤丹參組較單獨使用丹參組各項指標改變更明顯,兩組差異有統計學意義(P＜0.01).結論 還原型穀胱甘肽聯閤丹參箔療脂肪肝效果良好,值得臨床中廣汎推廣使用,利用肝髒CT值這一指標觀察藥物療效目前尚處于初步探討階段,值得進一步研究.
목적 탐토환원형곡광감태연합단삼치료지방간적료효급CT소묘재료효관찰중적정량작용.방법 대38례지방간병인진행환원형곡광감태연합단삼치료,관찰치료전후간공、혈지급간장CT치적변화정황.결과 치료후곡병전안매(ALT)유원래(205.4±9.7)U/L하강위(87.4±5.3)U/L,총담고순(TC)종(7.8±1.3)mmol/L하강위(4.2±1.0)mmol/L,감유삼지(TG)유(2.7±0.3)mmol/L강위(1.6±0.3)mmol/L,간장CT치유원래(26±8)Hu,증고지(37±11)Hu,치료전후대비유통계학의의(P＜0.01),환원형곡광감태연합단삼조교단독사용단삼조각항지표개변경명현,량조차이유통계학의의(P＜0.01).결론 환원형곡광감태연합단삼박료지방간효과량호,치득림상중엄범추엄사용,이용간장CT치저일지표관찰약물료효목전상처우초보탐토계단,치득진일보연구.
Objective To study the efficacy of treating fatty liver with reduced glutathione and Danshen root,and computed tomography was applied for quantitative measurement of efficacy.Methods 38 patients with fatty liver disease were treated with reduced glutathione and Danshen root for 4 weeks,before and after treatment liver function,serum lipid and imaging change were observed.Results Serum ALT reduced from (205.4±9.7) U/L to (87.4±5.3) U/L,TC reduced from (7.8±1.3) mmol/L to (4.2±1.0) mmol/L,TG reduced from (2.7±0.3) mmol/L to (1.6±0.3) mmol/L,after treatment,attenuation of liver have raised from (26±8) Hu to (37±11) Hu after treatment,all values before and after treatment have significant difference (P＜0.01).Conclusion Reduced Glutathione and Danshen Root have favorable results in treating fatty liver disease and worthy of clinical application,attenuation of liver can be applied for quantitative measurement of efficacy and worthy of further study.
