CAJ | 학술논문

目的收集并分析近年来我国克罗恩病(CD)的发病情况及时代变迁.方法对2003至2007年"中国生物医学文献数据库"(CBM)和全国性会议交流的所有CD相关描述性流行病学资料进行检索、复习及分析,并与既往50余年(1950至2002年)的系统分析结果进行比较.结果共收集到2003至2007年相关文献417篇,根据纳入及排除标准最终62篇资料入选,包含2149例CD患者[男1288例,女861例;男女比例为1.50∶1,年龄为2.5～86(39.9.4±2.2)岁].本研究中2003至2007年报道的CD患者例数是1950至2002年(1526例)的1.41倍,发病年龄(仍以中青年患者为主)与性别之比(仍男性多于女性)无明显变化.推算2003至2007年我国的CD平均发病率及患病率分别为1.21/10万人年与2.29/10万,均比1950至2002年的相应数据(0.28/10万人年与1.38/10万)增高.结论我国大陆地区CD患者近年来进一步增多,似呈快速上升趋势,但仍低于西方国家.
목적 수집병분석근년래아국극라은병(CD)적발병정황급시대변천.방법 대2003지2007년"중국생물의학문헌수거고"(CBM)화전국성회의교류적소유CD상관묘술성류행병학자료진행검색、복습급분석,병여기왕50여년(1950지2002년)적계통분석결과진행비교.결과 공수집도2003지2007년상관문헌417편,근거납입급배제표준최종62편자료입선,포함2149례CD환자[남1288례,녀861례;남녀비례위1.50∶1,년령위2.5～86(39.9.4±2.2)세].본연구중2003지2007년보도적CD환자례수시1950지2002년(1526례)적1.41배,발병년령(잉이중청년환자위주)여성별지비(잉남성다우녀성)무명현변화.추산2003지2007년아국적CD평균발병솔급환병솔분별위1.21/10만인년여2.29/10만,균비1950지2002년적상응수거(0.28/10만인년여1.38/10만)증고.결론 아국대륙지구CD환자근년래진일보증다,사정쾌속상승추세,단잉저우서방국가.
Objective To collect data and analyze the current status and prevalence changes of Crohn's disease (CD) in mainland China in recent decades. Methods A computer-based literature search was previously performed by using 50-year (1950 to 2002) of records of CD from the Chinese Database of Biology and Medicine (CBM) (1979 to 2002) and a manual year-by-year search of the literature ( 1950 to 1978). Using similar method, descriptive epidemiological data from 2003 to 2007 were collected, analyzed and compared with previous research. Results Four hundred and seventeen relevant papers during 2003 and 2007 were collected and 62 papers were eligible for inclusion. Within 62 papers, a total of 2149 cases with CD from 2003 to 2007 have been reported nationwide, comprising 1288 male and 861 female patients, result (ie,1526 cases from 1950-2002). There were no obvious changes in incidence age (younger and middle age were main components) and sex ratio ( number of male was still larger than that of female). The extrapolated CD incidence and prevalence rates were 1.21/100 000 person ? year and 2.29/100 000, respectively, which were higher than that of year 1950-2002, 0.28/100 000 person ? year and 1.38/ 100 000, respectively. Conclusions The incidence and prevalence rates of CD have been increasing rapidly, but these rates are still lower than those in Western world.