CAJ | 학술논문

目的探讨川芎嗪关节腔内注射治疗膝关节骨性关节的临床效果.方法将60例膝关节骨性关节炎患者随机分成治疗组和对照组,每组30例.治疗组行关节镜下关节清理术并腔内注射川芎嗪;对照组关节镜下关节清理术并腔内注射透明质酸钠.采用日本整形协会(JOA)制定的评定标准,于术后1周、3个月、6个月、12个月做疗效评定;并检测术前、术后1、10、20 d血清C-反应蛋白(CRP)的含量.结果术后1周两组无显著差异(P＞0.05);术后3个月、6个月、12个月治疗组疗效明显优于对照组,差异非常显著(P＜0.01);治疗组术后10 dCRP含量明显低于对照组,有非常显著差异(P＜0.01).结论川芎嗪关节腔内注射是治疗膝关节骨性关节炎的有效方法.
목적 탐토천궁진관절강내주사치료슬관절골성관절적림상효과.방법 장60례슬관절골성관절염환자수궤분성치료조화대조조,매조30례.치료조행관절경하관절청리술병강내주사천궁진;대조조관절경하관절청리술병강내주사투명질산납.채용일본정형협회(JOA)제정적평정표준,우술후1주、3개월、6개월、12개월주료효평정;병검측술전、술후1、10、20 d혈청C-반응단백(CRP)적함량.결과 술후1주량조무현저차이(P＞0.05);술후3개월、6개월、12개월치료조료효명현우우대조조,차이비상현저(P＜0.01);치료조술후10 dCRP함량명현저우대조조,유비상현저차이(P＜0.01).결론 천궁진관절강내주사시치료슬관절골성관절염적유효방법.
Objective To study the therapeutic effect of injecting chuanqiongqin in treating knee osteoarthritis.Methods 60 cases of knee osteoarthritis were divided into two groups randomly: treating group and control group,30 cases in a group.The treating group were treated by arthroscopic operation cooperated with injecting chuanqiongqin; the control group were given hyaluronate-NA weeks after received knee bone arthritis.The operation evaluation criteria of JOA was taken to value the therapeutic effect atl week,3 month,6 months and 12 months postoperation.At the same time,CRP(C-reactive protein)content in serum were measured at preoperation,1 day,10 days,20 days postoperation.Results At 1 week postoperation,there were no apparent differences(P ＞ 0.05) between the 2 groups.at 3 month,6 months and 12 months postoperation,the therapeutic effect of the treating group was much better than that of the control group,there were significant differences(P ＜0.01)between the 2 groups; At 10 days postoperation,the serum CRP content in the treating group was much lower than that of the control group,there were significant differences (P ＜ 0.01)between the 2 groups.Conclusion Injecting chuanqiongqin in treating knee osteoarthritis should be valid methods in treating knee osteoarthritis.