CAJ | 학술논문

目的探讨冠心病PCI术后支架内再狭窄(ISR)与尿微量白蛋白(MAU)的关系.方法选取2008年12月至2009年12月160例行PCI治疗并于1年[平均随访(10.2±2.5)个月]内再次行冠状动脉造影术(CAG)检查的冠心痛患者.通过术前MAU的测定及术后1年内的冠状动脉造影检查支架内再狭窄与否的结果,分为无再狭窄组(NISR)(作为对照组)及再狭窄组(ISR).依据再狭窄组中植入支架的血管支数,分为单支组、双支组、三支组.结果 ISR组MAU水平(60±19) mg/L,较NISR组(41±17) mg/L明显增高(t=5.109,P＜0.05)；ISR组三支组MAU水平(83±12) mg/L较双支组(58±7) mg/L明显增高(P＜0.05),双支组MAU水平较单支组(38.9±2.0) mg/L明显增高(P＜0.05).结论尿微量白蛋白可能是预测PCI术后支架内再狭窄的一个指标.
목적 탐토관심병PCI술후지가내재협착(ISR)여뇨미량백단백(MAU)적관계.방법 선취2008년12월지2009년12월160례행PCI치료병우1년[평균수방(10.2±2.5)개월]내재차행관상동맥조영술(CAG)검사적관심통환자.통과술전MAU적측정급술후1년내적관상동맥조영검사지가내재협착여부적결과,분위무재협착조(NISR)(작위대조조)급재협착조(ISR).의거재협착조중식입지가적혈관지수,분위단지조、쌍지조、삼지조.결과 ISR조MAU수평(60±19) mg/L,교NISR조(41±17) mg/L명현증고(t=5.109,P＜0.05)；ISR조삼지조MAU수평(83±12) mg/L교쌍지조(58±7) mg/L명현증고(P＜0.05),쌍지조MAU수평교단지조(38.9±2.0) mg/L명현증고(P＜0.05).결론 뇨미량백단백가능시예측PCI술후지가내재협착적일개지표.
Objective To study the relationship between in -stent restenosis (ISR) after percutaneous coronary intervention (PCI) and the concentration of microabluminuria (MAU) in patients with coronary heart disease.Methods One hundred and sixty patients underwent PCI and double check with coronary angiography (CAG) after about one year [ mean ( 10.2 ± 2.5 ) months ] were enrolled ; MAU was measured before PCI operation. Based on the secondary CAG results,all patients were divided into non- in- stent restenosis group (NISR) (as the control group) and in- stent restenosis group (ISR).According to the number of vessels of stent planted,patients in ISR were subdivided into single -vessel subgroup,double - vessel subgroup and three - vessel subgroup.Results Compared with NISR group,the level of MAU in ISR group was significantly higher[ (60 ± 19)mg/L VS (41 ± 17)mg/L] ( t =5.109,P ＜ 0.05).In ISR subgroups analysis,the level of MAU in three -vessel subgroup was highest [ (83 ± 12)mg/L] among the three subgroups ( P ＜ 0.05).And the level of MAU in double -vessel subgroup [ (58 ± 7 ) mg/L ] was higher than that in single - vessel subgroup [ ( 38.9 ± 2.0) mg/L ] ( P ＜0.05).Conclusions MAU might be an useful indicator for predicting ISR after PCI.