CAJ | 학술논문

目的探讨胰腺浆液性微囊性腺瘤的临床病理特征及其诊断与鉴别诊断.方法对7例胰腺浆液性微囊性腺瘤病例的临床资料、病理形态、免疫组化进行分析.结果 7例患者均为女性,平均年龄51岁,有临床症状者2例(28.6％).镜下肿瘤主要由大小不等的囊腔组成,囊壁衬覆单层立方上皮,细胞胞质透明并富含糖原.上皮细胞核小而圆,居中,无核仁,无核分裂象.部分囊腔之间可见粗大的纤维组织分隔.免疫组化上皮细胞AE1/AE3、CK7、CK8、CK19、CK/LMW、EMA(+)；CEA、CD31、CD34、D2-40、Syn、CgA、Calretinin、Vim(一).结论胰腺浆液性微囊性腺瘤是一种较为少见的良性肿瘤,老年女性好发,预后好,确诊主要靠术后病理组织学和免疫组化.
목적 탐토이선장액성미낭성선류적림상병리특정급기진단여감별진단.방법 대7례이선장액성미낭성선류병례적림상자료、병리형태、면역조화진행분석.결과 7례환자균위녀성,평균년령51세,유림상증상자2례(28.6％).경하종류주요유대소불등적낭강조성,낭벽츤복단층립방상피,세포포질투명병부함당원.상피세포핵소이원,거중,무핵인,무핵분렬상.부분낭강지간가견조대적섬유조직분격.면역조화상피세포AE1/AE3、CK7、CK8、CK19、CK/LMW、EMA(+)；CEA、CD31、CD34、D2-40、Syn、CgA、Calretinin、Vim(일).결론 이선장액성미낭성선류시일충교위소견적량성종류,노년녀성호발,예후호,학진주요고술후병리조직학화면역조화.
Objective To study the clinicopathological features in the diagnosis of serous microcystic adenoma of pancreas.Method A clinicopathological and immunohistochemical study was conducted on 7 patients with serous microcystic adenoma of pancreas.Results All the patients were female,with a mean age of 51 years.Clinical symptoms were present in 2(28.6％)patients.On microscopy,the tumor composed of variable-sized cysts.The cyst wall was covered by simple cuboidal epithelium.The cytoplasm was clear and glycogen-rich.The nucleus of the epithelial cells was small and round.In the center,there was no nucleolus and no nuclear division.There were bulky fibrous tissues between the cystic cavities.Immunohistochemical study showed AE1/AE3,CK7,CK8,CK19,CK/LMW,EMA were positive,and CEA,CD31,CD34,D2-40,Syn,CgA,Calretinin,Vim were negative.Conclusions Serous microcystic adenoma of pancreas is a rare tumor,which was common in old women.Serous microcystic adenoma of pancreas is a benign tumor with good prognosis.The diagnosis is made on histopathological and immunohistochemical study.