中国基层医药
中國基層醫藥
중국기층의약
CHINESE JOURNAL OF PRIMARY MEDICINE AND PHARMACY
2011年
15期
2033-2034
,共2页
甲状腺肿瘤%甲状激素%手术后并发症
甲狀腺腫瘤%甲狀激素%手術後併髮癥
갑상선종류%갑상격소%수술후병발증
Thyroid Neoplasms%Thyroxiue%Postoperative Complications
目的 了解甲状腺不同手术方式对术后甲状腺激素水平的影响，为术后替代治疗提供依据。方法 对120例甲状腺腺瘤采取单纯腺瘤切除术30例，单侧腺叶切除术，30例，双侧次全切除术30例，全切除术30例，观察比较不同手术方式治疗的甲状腺手术前、手术后第10天、1个月、3个月血清甲状腺激素水平。结果 单纯腺瘤切除术前后FT3、FT4水平没有变化、单侧腺叶切除术后FT3、FT4水平在第10天时出现一过性降低(P＜0.01)；双侧次全切除术后第10天及1个月FT3、FT4均低于术前水平(P＜0.01)，3个月后恢复到术前水平；全切术后患者口服甲状腺素片维持，甲状腺激素水平与术前差异无统计学意义。结论 甲状腺单侧腺叶切除，双侧次全切除及全切均会不同程度的在某一时间段引起甲状腺激素水平降低，需要给予适当的替代治疗。
目的 瞭解甲狀腺不同手術方式對術後甲狀腺激素水平的影響，為術後替代治療提供依據。方法 對120例甲狀腺腺瘤採取單純腺瘤切除術30例，單側腺葉切除術，30例，雙側次全切除術30例，全切除術30例，觀察比較不同手術方式治療的甲狀腺手術前、手術後第10天、1箇月、3箇月血清甲狀腺激素水平。結果 單純腺瘤切除術前後FT3、FT4水平沒有變化、單側腺葉切除術後FT3、FT4水平在第10天時齣現一過性降低(P＜0.01)；雙側次全切除術後第10天及1箇月FT3、FT4均低于術前水平(P＜0.01)，3箇月後恢複到術前水平；全切術後患者口服甲狀腺素片維持，甲狀腺激素水平與術前差異無統計學意義。結論 甲狀腺單側腺葉切除，雙側次全切除及全切均會不同程度的在某一時間段引起甲狀腺激素水平降低，需要給予適噹的替代治療。
목적 료해갑상선불동수술방식대술후갑상선격소수평적영향，위술후체대치료제공의거。방법 대120례갑상선선류채취단순선류절제술30례，단측선협절제술，30례，쌍측차전절제술30례，전절제술30례，관찰비교불동수술방식치료적갑상선수술전、수술후제10천、1개월、3개월혈청갑상선격소수평。결과 단순선류절제술전후FT3、FT4수평몰유변화、단측선협절제술후FT3、FT4수평재제10천시출현일과성강저(P＜0.01)；쌍측차전절제술후제10천급1개월FT3、FT4균저우술전수평(P＜0.01)，3개월후회복도술전수평；전절술후환자구복갑상선소편유지，갑상선격소수평여술전차이무통계학의의。결론 갑상선단측선협절제，쌍측차전절제급전절균회불동정도적재모일시간단인기갑상선격소수평강저，수요급여괄당적체대치료。
Objective To investigate changes of the level of serum thyroxine after different style operation on thyroid gland,for guiding replacement therapy after surgery. Methods To select patients randomly,include the excision of adenoma of thyroid、the lobectomy of unilateral thyroid、the subtotal ectomy of bilateral thyroid and total resection of bilateral thyroid quaque forty,among the total,the patients who suffererd the total resection of bilateral thyroid take thyroxine 40mg bid orally everyday. To detect the serum thyroxine in all of the patients, when preoperation、ten days after operation、one month after operation and three months after operation. Results The serum thyroxine in patients who suffererd the excision of adenoma of thyroid were had no marked changes compare to preoperation; Serum FT3 、FT4 in patients suffer the lobectomy of unilateral thyroid are lower than preoperation when ten days after operation (P＜0.01) ;Serum FT3、FT4 in patients sufferred subtotal ectomy of bilateral thyroid were lower than preoperation,when ten days after operation and one month after operation( P ＜ 0.01 ), then returned to the level of preoperation when three months after operation;the serum thyroxine of patients who sufferred the total resection of bilateral thyroid had no marked changes compare to preoperation,when they taker thyroxine 40mg bid orally everyday. Conclusion The serum thyroxine level of patients who suffer the lobectomy of unilateral thyroid、the subtotal ectomy of bilateral thyroid and total resection of bilateral thyroid is lower than preoperation at different degree, they should be given replacement therapy properly.
