CAJ | 학술논문

目的探讨糖尿病并发短暂性脑缺血发作(TIA)患者血脂、血清高敏C反应蛋白(hs-CRP)与预后的关系.方法选择80例糖尿病并发TIA首次发作患者,对其随访1年,其中31例糖尿病并发2～4次TIA(B组),6例发生缺血性卒中(C组),余43例随访中未再发生TIA及缺血性卒中(A组);另选择40例糖尿病无TIA者作为对照组.检测各组患者血脂及血清hs-CRP水平.结果 A、B、C组患者血清总胆固醇(TC)、低密度脂蛋白胆固醇(LDL-C)、hs-CRP水平均显著高于对照组,差异有统计学意义(P＜0.01);B、C组患者血清TC、LDL-C、hs-CRP水平显著高于A组,差异有统计学意义(P＜0.05);C组患者血清TC、LDL-C、hs-CRP水平又显著高于B组,差异有统计学意义(P＜0.05).结论血脂及hs-CRP水平可作为判断糖尿病并发TIA患者预后的指标;血脂、血清hs-CRP水平升高,提示糖尿病并发TIA患者预后较差.
목적 탐토당뇨병병발단잠성뇌결혈발작(TIA)환자혈지、혈청고민C반응단백(hs-CRP)여예후적관계.방법 선택80례당뇨병병발TIA수차발작환자,대기수방1년,기중31례당뇨병병발2～4차TIA(B조),6례발생결혈성졸중(C조),여43례수방중미재발생TIA급결혈성졸중(A조);령선택40례당뇨병무TIA자작위대조조.검측각조환자혈지급혈청hs-CRP수평.결과 A、B、C조환자혈청총담고순(TC)、저밀도지단백담고순(LDL-C)、hs-CRP수평균현저고우대조조,차이유통계학의의(P＜0.01);B、C조환자혈청TC、LDL-C、hs-CRP수평현저고우A조,차이유통계학의의(P＜0.05);C조환자혈청TC、LDL-C、hs-CRP수평우현저고우B조,차이유통계학의의(P＜0.05).결론 혈지급hs-CRP수평가작위판단당뇨병병발TIA환자예후적지표;혈지、혈청hs-CRP수평승고,제시당뇨병병발TIA환자예후교차.
Objective To explore the relationship between levels of serum lipid,high sensitive C-reactive protein(hs-CRP) and prognosis of patients with diabetes mellitus merger transient ischemic attacks(TIA).Methods During 1 year follow-up period,to observe diabetes mellitus merger TIA first attacked 43 cases (A group);diabetes mellitus merger more than twice attacked 31 cases (B group);6 cases developed ischemic stroke (C group);diabetes mellitus 40 cases,and none of patients with TIA as control group.Lipid and hs-CRP in serum was detected in 24 hours for 80 patients and 40 controls.Results Serum lipid and hs-CRP level of group A,B,C,were higher than control group(P＜0.01);serum lipid and and-CRP level of patients in group B and C,were much higher than group A(P＜0.05);serum lipid and hs-CRP in serum of patients in group C,were much higher than group B(P＜0.05).Conclusion Serum lipid and hs-CRP are useful index for diabetes mellitus merger TIA patients,and high seral level of serum lipid and hs-CRP may predicate relatively higher recurrence.