化学通报(印刷版)
化學通報(印刷版)
화학통보(인쇄판)
CHEMISTRY
2010年
2期
111-117
,共7页
王小波%叶能胜%王继芬%谷学新
王小波%葉能勝%王繼芬%穀學新
왕소파%협능성%왕계분%곡학신
可卡因%代谢物%生物检材
可卡因%代謝物%生物檢材
가잡인%대사물%생물검재
Cocaine%Metabolites%Biological samples
综述了近十年来生物检材中可卡因及其代谢物分析常用的样品前处理技术和检测方法,比较了液-液萃取、固相萃取、固相微萃取等提取方法的可行性和局限性及气相色谱、气相色谱-质谱联用、液相色谱-质谱联用等检测方法的应用进展.
綜述瞭近十年來生物檢材中可卡因及其代謝物分析常用的樣品前處理技術和檢測方法,比較瞭液-液萃取、固相萃取、固相微萃取等提取方法的可行性和跼限性及氣相色譜、氣相色譜-質譜聯用、液相色譜-質譜聯用等檢測方法的應用進展.
종술료근십년래생물검재중가잡인급기대사물분석상용적양품전처리기술화검측방법,비교료액-액췌취、고상췌취、고상미췌취등제취방법적가행성화국한성급기상색보、기상색보-질보련용、액상색보-질보련용등검측방법적응용진전.
The sample pre-treatment technologies and determination methods for cocaine and its metabolites in biological specimens were reviewed.The feasibility and limitations of extraction methods,such as liquid-liquid extraction,solid phase extraction,solid-phase microextraction were compared,and the application progress of determination methods such as GC,GC/MS and LC/MS were introduced.