CAJ | 학술논문

目的观察不同年龄组正常腮腺α-淀粉酶、溶菌酶的分布、含量及增龄性变化的规律。方法将51例腮腺标本分为4个年龄组，用免疫组化的方法标记α-淀粉酶、溶菌酶，观察记录不同年龄组α-淀粉酶、溶菌酶的染色强度。结果 4个年龄组之间α-淀粉酶、溶菌酶染色阳性率差异有显著性，随着年龄增长，其染色阳性率呈逐渐减低的趋势。结论 HE切片上染色、形态相似的浆液性腺泡之间，实际在功能上存在着很大的不同。α-淀粉酶、溶菌酶增龄性变化的特点与定量组织学研究结果相符合。
목적관찰불동년령조정상시선α-정분매、용균매적분포、함량급증령성변화적규률。방법장51례시선표본분위4개년령조，용면역조화적방법표기α-정분매、용균매，관찰기록불동년령조α-정분매、용균매적염색강도。결과 4개년령조지간α-정분매、용균매염색양성솔차이유현저성，수착년령증장，기염색양성솔정축점감저적추세。결론 HE절편상염색、형태상사적장액성선포지간，실제재공능상존재착흔대적불동。α-정분매、용균매증령성변화적특점여정량조직학연구결과상부합。
Objective　To investigate the aging changes, the distribution and the content of α-amylase、lysozyme in the normal parotid glands. Methods　Fifty-one specimens of parotid glands with 4 different age groups were studied by immunohistochemical method. The intensity of staining of α-amylase、lysozyme was recorded in different age groups. Results　The staining positivity rate of α-amylase、lysozyme had striking differences in 4 different age groups and it gradually decreased along with the age increasing. Conclusions　There are differences among seous acinus which had similar shape and staining in HE slice. The characters of aging changes of α-amylase、lysozyme secreted by acinar and intercalated duct cells are conformity with the results of quantitative studies in histology.