沈阳药科大学学报
瀋暘藥科大學學報
침양약과대학학보
JOURNAL OF SHENYANG PHARMACEUTICAL UNIVERSIT
2001年
3期
211-212
,共2页
李伟东%阚毓铭%洪敏%朱荃
李偉東%闞毓銘%洪敏%硃荃
리위동%감육명%홍민%주전
刺果甘草%后莫紫檀素%美迪紫檀素%人肝癌细胞(Hep-2)
刺果甘草%後莫紫檀素%美迪紫檀素%人肝癌細胞(Hep-2)
자과감초%후막자단소%미적자단소%인간암세포(Hep-2)
观察刺果甘草活性成分后莫紫檀素(homopterocarpin)、美迪紫檀素(medicarpin)的体外抗癌活性,通过人肝癌细胞(Hep-2)进行体外实验,结果表明它们均有抑制和杀灭人肝癌细胞的作用,并且美迪紫檀素的作用强于后莫紫檀素。此2个单体化合物是刺果甘草的活性成分。
觀察刺果甘草活性成分後莫紫檀素(homopterocarpin)、美迪紫檀素(medicarpin)的體外抗癌活性,通過人肝癌細胞(Hep-2)進行體外實驗,結果錶明它們均有抑製和殺滅人肝癌細胞的作用,併且美迪紫檀素的作用彊于後莫紫檀素。此2箇單體化閤物是刺果甘草的活性成分。
관찰자과감초활성성분후막자단소(homopterocarpin)、미적자단소(medicarpin)적체외항암활성,통과인간암세포(Hep-2)진행체외실험,결과표명타문균유억제화살멸인간암세포적작용,병차미적자단소적작용강우후막자단소。차2개단체화합물시자과감초적활성성분。
An observation on the anticancer activity of homopterocarpin and medicarpin in vitro,which was separated from the root of Glycyrrhiza pallidiflora Maxim.. The cell culture test was used in these studies in vitro. The experimental result showed that these two ingredients could inhibite(lower concentration) or kill(higher concentration) human's liver cancer cells under the cultured condition, moreover, the effect of medicarpin was stronger than that of homopterocarpin.These two monomers were active components of Glycyrrhiza pallidiflora Maxim.