临床儿科杂志
臨床兒科雜誌
림상인과잡지
2001年
2期
70-71，77
,共3页
新生儿%一氧%化氮%谷氨酸%缺氧缺血性脑病
新生兒%一氧%化氮%穀氨痠%缺氧缺血性腦病
신생인%일양%화담%곡안산%결양결혈성뇌병
为探讨脑脊液谷氨酸和一氧化氮(NO)水平变化 在新 生儿缺氧缺血性脑病(HIE)中的作用及相互关系，对24例HIE新生儿脑脊液谷氨酸和NO水平进 行检测， 并与8例对照组比较。结果：中、 重度HIE组脑脊液谷氨酸和NO 水平明显高于 对照组及轻度HIE组； 谷氨酸和NO呈显著正相关。提示谷氨酸和NO在新生儿HIE的 发生和发展 过程中具有重要意义。
為探討腦脊液穀氨痠和一氧化氮(NO)水平變化 在新 生兒缺氧缺血性腦病(HIE)中的作用及相互關繫，對24例HIE新生兒腦脊液穀氨痠和NO水平進 行檢測， 併與8例對照組比較。結果：中、 重度HIE組腦脊液穀氨痠和NO 水平明顯高于 對照組及輕度HIE組； 穀氨痠和NO呈顯著正相關。提示穀氨痠和NO在新生兒HIE的 髮生和髮展 過程中具有重要意義。
위탐토뇌척액곡안산화일양화담(NO)수평변화 재신 생인결양결혈성뇌병(HIE)중적작용급상호관계，대24례HIE신생인뇌척액곡안산화NO수평진 행검측， 병여8례대조조비교。결과：중、 중도HIE조뇌척액곡안산화NO 수평명현고우 대조조급경도HIE조； 곡안산화NO정현저정상관。제시곡안산화NO재신생인HIE적 발생화발전 과정중구유중요의의。
To explore the role of cerebro-spinal flu id(CSF)glutamate and nitric oxide (NO) in the pathogenesis of neonatal hypoxic- ischemia encephalopathy (HIE), glutamate and NO in CSF were determined in 24 new born infants with HIE and 8 normal control infants, respectively. The results sh owed that the levels of glutamate and NO in CSF were significantly higher in the neonates with moderate and severe HIE than those in both of the control group an d neonates with mild HIE.There was an obviously positive relationship between le v els of glutamate and NO. It is concluded that glutamate and NO play an important role in the pathogenesis of neonatal HIE.
