CAJ | 학술논문

目的调查成人红细胞压积是否有季节性变化，并探讨其临床意义。方法 93～97年检测15，178例中、老年男、女性成人红细胞压积值，对其与多种气象要素(气温、相对湿度、气压)作相关性分析。结果男、女性成人红细胞压积及其阳性率均存在显著季节性差异，(P＜0.01)。各季红细胞压积均值与气温及相对湿度呈直线负相关(r分别为男：-0.642，-0.573；女：-0.682，-0.610)，与气压呈直线正相关(r分别为男：0.647；女：0.673)(均P＜0.01)。结论受气象条件变化影响红细胞压积具有季节性变化，可能是缺血性心、脑血管疾病的血液流变学影响机制之一。
목적조사성인홍세포압적시부유계절성변화，병탐토기림상의의。방법 93～97년검측15，178례중、노년남、녀성성인홍세포압적치，대기여다충기상요소(기온、상대습도、기압)작상관성분석。결과남、녀성성인홍세포압적급기양성솔균존재현저계절성차이，(P＜0.01)。각계홍세포압적균치여기온급상대습도정직선부상관(r분별위남：-0.642，-0.573；녀：-0.682，-0.610)，여기압정직선정상관(r분별위남：0.647；녀：0.673)(균P＜0.01)。결론수기상조건변화영향홍세포압적구유계절성변화，가능시결혈성심、뇌혈관질병적혈액류변학영향궤제지일。
Objective To investigate the relationship between seasonal variation of hematocrit and its clinical significance. Method Hematocrit of 15,178 subjects in observation group and 150 healthy adults in control group were examined in different seasons from 1993 to 1997 for statistical analysis. Results hematocrit of both male and female adults has significant seasonal difference, and it shows liner relationship with temperature, relative humidity and atmospheric pressure. Conclusion Seasonal variation of hematocrit caused by the effect of climate condition may be one plausible hemorheological mechanism that may be associated with seasonal variation of morbidity and mortality of ischemic cardio and cerebrovascular diseases.