中国烧伤创疡杂志
中國燒傷創瘍雜誌
중국소상창양잡지
2001年
1期
42-44
,共3页
内皮素%肌酸激酶同工酶%严重烧伤%心肌损害
內皮素%肌痠激酶同工酶%嚴重燒傷%心肌損害
내피소%기산격매동공매%엄중소상%심기손해
目的：探讨血浆内皮素(ET)变化与烧伤早期心肌损害的关系。方法：采用放免法检测5例严重烧伤病人烧伤早期血浆ET和ASCA仪测定血浆肌酸激酶同工酶(CK－MB)。结果：伤后12h血浆ET（106.0±1.6pg/ml，n=5）较正常人组（47.6±3.4pg/ml，n=8）明显升高。血浆CK－MB在伤后明显升高。相关分析显示，ET升高与CK－MB呈高度正相关。结论：血浆ET升高可能参与了烧伤早期的心肌损害。
目的：探討血漿內皮素(ET)變化與燒傷早期心肌損害的關繫。方法：採用放免法檢測5例嚴重燒傷病人燒傷早期血漿ET和ASCA儀測定血漿肌痠激酶同工酶(CK－MB)。結果：傷後12h血漿ET（106.0±1.6pg/ml，n=5）較正常人組（47.6±3.4pg/ml，n=8）明顯升高。血漿CK－MB在傷後明顯升高。相關分析顯示，ET升高與CK－MB呈高度正相關。結論：血漿ET升高可能參與瞭燒傷早期的心肌損害。
목적：탐토혈장내피소(ET)변화여소상조기심기손해적관계。방법：채용방면법검측5례엄중소상병인소상조기혈장ET화ASCA의측정혈장기산격매동공매(CK－MB)。결과：상후12h혈장ET（106.0±1.6pg/ml，n=5）교정상인조（47.6±3.4pg/ml，n=8）명현승고。혈장CK－MB재상후명현승고。상관분석현시，ET승고여CK－MB정고도정상관。결론：혈장ET승고가능삼여료소상조기적심기손해。
Objective: To study the effect of plasma endothelin (ET) level on myocardial injury of severely burned patients. Method: Plasma ET level was determined by radio－ immunoassay and plasma levels of CK-MB by automatic serum biochemical assay. Result: Plasma ET level increased significantly 12 hr post burn as compared with normal persons (P<0.01), plasma CK MB increased significantly within first 24 hr post burn. Plasma ET level was positive correlated to CK MB level. Conclusion: The results suggested that elevated plasma ET level may be involved in the damage of myocardium in the early stage of severe burn.
