CAJ | 학술논문

观察5种植物油在高脂血症形成过程中对大鼠血脂和脂质过氧化的影响。在高脂饲料中分别加入6%的猪油、松籽油、紫苏油、黑加仑油、琉璃苣油和月见草油喂饲Wistar雄性成年大鼠3周，5种植物油组大鼠血清甘油三酯（TG）、总胆固醇（TC）、低密度脂蛋白胆固醇（LDL-C）、LDL-C与高密度脂蛋白胆固醇（HDL-C）比值（LDL-C/HDL-C）的增加值和HDL-C/TC、卵磷脂胆固醇酰基转移酶（LCAT）活性的下降均不同程度地低于单纯食猪油的高脂对照组。紫苏油、黑加仑油、琉璃苣油和月见草油可提高血清HDL-C、高密度脂蛋白亚组分Ⅱ胆固醇（HDL2-C）及HDL2-C与高密度脂蛋白亚组分Ⅲ胆固醇（HDL3-C）比值（HDL2-C/HDL3-C）。紫苏油、黑加仑油和月见草油组大鼠肝脏过氧化脂质（LPO）含量高于松籽油、琉璃苣油和猪油组。结果表明5种植物油均具有一定的调节血脂作用，松籽油和琉璃苣油的组织脂质过氧化物相对较低。
관찰5충식물유재고지혈증형성과정중대대서혈지화지질과양화적영향。재고지사료중분별가입6%적저유、송자유、자소유、흑가륜유、류리거유화월견초유위사Wistar웅성성년대서3주，5충식물유조대서혈청감유삼지（TG）、총담고순（TC）、저밀도지단백담고순（LDL-C）、LDL-C여고밀도지단백담고순（HDL-C）비치（LDL-C/HDL-C）적증가치화HDL-C/TC、란린지담고순선기전이매（LCAT）활성적하강균불동정도지저우단순식저유적고지대조조。자소유、흑가륜유、류리거유화월견초유가제고혈청HDL-C、고밀도지단백아조분Ⅱ담고순（HDL2-C）급HDL2-C여고밀도지단백아조분Ⅲ담고순（HDL3-C）비치（HDL2-C/HDL3-C）。자소유、흑가륜유화월견초유조대서간장과양화지질（LPO）함량고우송자유、류리거유화저유조。결과표명5충식물유균구유일정적조절혈지작용，송자유화류리거유적조직지질과양화물상대교저。
The effects of vegetable seed oil on hyperlipidemia induced byhigh lipid diet in rats. Male adult Wistar rats were fed on the test diet containing 94% high lipid diet and 6% lard pinon seed oil, perilla seed oil, blackcurrent seed oil, borage seed oil and evening primrose seed oil respectively for 3 weeks. The results showed that the vale of trilyceride(TG), total cholesterol(TC),low density lipoprotein cholesterol(LDL-C), LDL-C/HDL-C(high density lipoprotein cholesterol)ratio increased and the vale of HDL-C/TC ratio and lecithin-cholesterol acyltransferase(LCAT)activity decreased in the groups with vegetable seed oil were less than that of the control group. The results suggested that all the five kinds of vegetable seed oil had the effect of regulating lipid metabolism of hyperlipidemia rats to some extent. Pinon seed oil and borage seed oil may be well suited for the prevention of atherosclerosis.