CAJ | 학술논문

绿色化学和社会可持续发展需求对物质加工手段提出了更高要求.生物催化和化学催化的交叉整合可以实现两种技术的优势互补,从而提高原子效率,减轻环境压力,降低生产成本,在精细(手性)化学品合成新工艺的开发和工业化生产中具有十分广阔的应用前景.生物催化和化学催化的交叉需要生物学家和化学家的紧密合作,着重解决生物催化和化学催化反应的相容性,生物催化反应类型的拓展及其分子催化机理的认识,及生物催化剂的快速商品化、工具化技术等问题.
록색화학화사회가지속발전수구대물질가공수단제출료경고요구.생물최화화화학최화적교차정합가이실현량충기술적우세호보,종이제고원자효솔,감경배경압력,강저생산성본,재정세(수성)화학품합성신공예적개발화공업화생산중구유십분엄활적응용전경.생물최화화화학최화적교차수요생물학가화화학가적긴밀합작,착중해결생물최화화화학최화반응적상용성,생물최화반응류형적탁전급기분자최화궤리적인식,급생물최화제적쾌속상품화、공구화기술등문제.
There is growing interest in sustainable solutions for social development in the long term. Combination of biocatalysis and chemocatalysis can deliver atom economic, cost effective and environmental friendly alternative tools, and has find wide application in the commercial manufacture of fine (chiral) chemicals. Integration of biocatalysis and chemocatalysis needs closer cooperation of chemist and biotechnologist. Successful problem solution of the integration will come from the following three aspects: compatible of biocatalysis and chemocatalysis reactions, exploiting of novel biocatalysis reaction type and understanding of the molecular mechanisms, and rapid commercialization of biocatalyst.