CAJ | 학술논문

患者女,60岁,因面部结节、斑块1年余就诊.患者以面部结节和浸润性斑块为皮损表现.皮肤科检查:前额见皮色和淡红色结节,左下颏见浸润性斑块,上覆黄色痂皮.组织病理检查示,真皮及皮下血管、附属器周围以淋巴细胞为主的炎症细胞浸润,毛囊上皮网状变性,并形成囊腔,经阿新蓝染色见囊腔中大量黏蛋白沉积.治疗方面给予阿维A和泼尼松口服,局部外用莫米松乳膏联合异维A酸凝胶等治疗,2个月后痊愈.
환자녀,60세,인면부결절、반괴1년여취진.환자이면부결절화침윤성반괴위피손표현.피부과검사:전액견피색화담홍색결절,좌하해견침윤성반괴,상복황색가피.조직병리검사시,진피급피하혈관、부속기주위이림파세포위주적염증세포침윤,모낭상피망상변성,병형성낭강,경아신람염색견낭강중대량점단백침적.치료방면급여아유A화발니송구복,국부외용막미송유고연합이유A산응효등치료,2개월후전유.
A case of follicular mucinosis is reported. A 60-year-old female was admitted to the hospital for facial nodules and infiltrated plaques over 1 year. Dermatological examination revealed skin-colored or pink nodules on the forehead and infiltrated plaques on the left chin covered with yellow crusts. The biopsy of a skin lesion demonstrated a mixed infiltrate of inflammatory cells which were predominated by lymphocytes, in dermis and around subcutaneous blood vessels and appendages. Reticular degeneration of follicular epithelial cells and formation of cysts were also observed. Alcian blue stain displayed massive mucin deposition in cyst cavity. After treatment with oral acitretin and prednisone and topical mometasone cream and isotretinoin gel for 2 months, the lesions disappeared.