中华耳鼻咽喉头颈外科杂志
中華耳鼻嚥喉頭頸外科雜誌
중화이비인후두경외과잡지
CHINESE JOURNAL OF OTORHINOLARYNGOLOGY HEAD AND NECK SURGERY
2010年
11期
895-898
,共4页
卢星%黄晓明%孙伟%梁蔚文%蔡谦
盧星%黃曉明%孫偉%樑蔚文%蔡謙
로성%황효명%손위%량위문%채겸
内窥镜检查%甲状腺切除术%随机对照试验
內窺鏡檢查%甲狀腺切除術%隨機對照試驗
내규경검사%갑상선절제술%수궤대조시험
Endoscopy%Thyroidectomy%Randomized controlled trials
目的 前瞻性随机对照研究经胸前人路的无注气内镜下甲状腺手术与传统甲状腺手术对机体的创伤大小.方法 选择2006年11月至2008年2月中山大学第二附属医院耳鼻咽喉头颈外科收治的甲状腺肿物患者采用系统随机化法将患者分为两组,内镜组:25例行经胸前人路的无注气内镜甲状腺手术;传统手术组:22例行传统甲状腺手术.统计分析两组患者围手术期不同时间血中白细胞计数(white blood cell count,WBC)、C反应蛋白(serum C-reative protein,CRP)、白细胞介素6(IL-6)水平的差异.结果 在术后12,24及48 h 3个时间点,两组间WBC的差异无统计学意义(t值分别为-0.172、1.774、2.039,P＞0.05),CRP的差异无统计学意义(t值分别为-0.927、-1.701、-1.813,P＞0.05),IL-6水平的差异无统计学意义(t值分别为0.098、-2.019、-1.121,P＞0.05).结论 经胸前人路的无注气内镜甲状腺手术对机体的创伤与传统手术相比虽未达到微创的标准,但并不增加对机体的创伤.
目的 前瞻性隨機對照研究經胸前人路的無註氣內鏡下甲狀腺手術與傳統甲狀腺手術對機體的創傷大小.方法 選擇2006年11月至2008年2月中山大學第二附屬醫院耳鼻嚥喉頭頸外科收治的甲狀腺腫物患者採用繫統隨機化法將患者分為兩組,內鏡組:25例行經胸前人路的無註氣內鏡甲狀腺手術;傳統手術組:22例行傳統甲狀腺手術.統計分析兩組患者圍手術期不同時間血中白細胞計數(white blood cell count,WBC)、C反應蛋白(serum C-reative protein,CRP)、白細胞介素6(IL-6)水平的差異.結果 在術後12,24及48 h 3箇時間點,兩組間WBC的差異無統計學意義(t值分彆為-0.172、1.774、2.039,P＞0.05),CRP的差異無統計學意義(t值分彆為-0.927、-1.701、-1.813,P＞0.05),IL-6水平的差異無統計學意義(t值分彆為0.098、-2.019、-1.121,P＞0.05).結論 經胸前人路的無註氣內鏡甲狀腺手術對機體的創傷與傳統手術相比雖未達到微創的標準,但併不增加對機體的創傷.
목적 전첨성수궤대조연구경흉전인로적무주기내경하갑상선수술여전통갑상선수술대궤체적창상대소.방법 선택2006년11월지2008년2월중산대학제이부속의원이비인후두경외과수치적갑상선종물환자채용계통수궤화법장환자분위량조,내경조:25례행경흉전인로적무주기내경갑상선수술;전통수술조:22례행전통갑상선수술.통계분석량조환자위수술기불동시간혈중백세포계수(white blood cell count,WBC)、C반응단백(serum C-reative protein,CRP)、백세포개소6(IL-6)수평적차이.결과 재술후12,24급48 h 3개시간점,량조간WBC적차이무통계학의의(t치분별위-0.172、1.774、2.039,P＞0.05),CRP적차이무통계학의의(t치분별위-0.927、-1.701、-1.813,P＞0.05),IL-6수평적차이무통계학의의(t치분별위0.098、-2.019、-1.121,P＞0.05).결론 경흉전인로적무주기내경갑상선수술대궤체적창상여전통수술상비수미체도미창적표준,단병불증가대궤체적창상.
Objective To evaluate the difference in surgical stress between gasless endoscoic thyroidectomy through anterior chest approach and conventional thyroidectomy. Methods The patients with thyroid nodules who would undergo thyroidectomy between November 2006 and February 2008 in Department of Otorhinolaryngology Head and Neck Surgery, Second Affiliated Hospital of Sun Yat-sen University, were randomly divided into gasless endoscopic thyroidectomy group or conventional thyroidectomy group, with 25 cases and 22 cases respectively. Before and after surgery, white blood cell count( WBC), serum C-reactive protein(CRP) and interleukin-6(IL-6) were measured to assess the surgical stress response. Results At 12 h, 24 h and 48 h after surgery, no significant difference was found between the two groups in WBC (t =- 0. 172, 1. 774 and 2. 039 respectively, P ＞ 0.05), serum CRP ( t = - 0. 927, - 1. 701 and - 1. 813,P＞0.05)and IL-6 (t =0.098, -2.019 and -1. 121, P＞0.05). Conclusion The stress response of gasless endoscopic thyroidectomy is similar with that of conventional thyroidectomy.
