国际医药卫生导报
國際醫藥衛生導報
국제의약위생도보
INTERNATIONAL MEDICINE & HEALTH GUIDANCE NEWS
2009年
2期
15-17
,共3页
难治性高血压%血液透析滤过%血液透析%甲状旁腺素%肾素%血管紧张素Ⅱ
難治性高血壓%血液透析濾過%血液透析%甲狀徬腺素%腎素%血管緊張素Ⅱ
난치성고혈압%혈액투석려과%혈액투석%갑상방선소%신소%혈관긴장소Ⅱ
Refractory hypertension%Hemodiafiltration%Hemodialysis%Parathyroid hormone Renin Angiotensin Ⅱ
目的 比较血液透析滤过与标准血液透析治疗慢性肾功能衰竭(CRF)患者难治性高血压的疗效及其机制探讨.方法 将60例CRF伴难治性高血压患者随机分为2组.A组(HD组)应用每周3次标准血液透析(HD)治疗;B组(HDF组)行每周1次常规标准血液透析(HD)治疗和每周2次血液透析滤过(HDF)治疗.比较两组患者治疗前及治疗后8周甲状旁腺素(iPTH)、血浆肾素(RA)、血管紧张素Ⅱ(Ang Ⅱ)、平均动脉压的变化.结果 B组患者iPTH、血浆肾素(RA)、血管紧张素Ⅱ(Ang Ⅱ)较A组均明显下降,平均动脉压亦下降更加显著.结论 血液透析滤过能有效地清除血浆RA、AngⅡ、甲状旁腺素(iPTH)等中分子毒素,治疗难治性高血压效果优于血液透析,值得临床推广.
目的 比較血液透析濾過與標準血液透析治療慢性腎功能衰竭(CRF)患者難治性高血壓的療效及其機製探討.方法 將60例CRF伴難治性高血壓患者隨機分為2組.A組(HD組)應用每週3次標準血液透析(HD)治療;B組(HDF組)行每週1次常規標準血液透析(HD)治療和每週2次血液透析濾過(HDF)治療.比較兩組患者治療前及治療後8週甲狀徬腺素(iPTH)、血漿腎素(RA)、血管緊張素Ⅱ(Ang Ⅱ)、平均動脈壓的變化.結果 B組患者iPTH、血漿腎素(RA)、血管緊張素Ⅱ(Ang Ⅱ)較A組均明顯下降,平均動脈壓亦下降更加顯著.結論 血液透析濾過能有效地清除血漿RA、AngⅡ、甲狀徬腺素(iPTH)等中分子毒素,治療難治性高血壓效果優于血液透析,值得臨床推廣.
목적 비교혈액투석려과여표준혈액투석치료만성신공능쇠갈(CRF)환자난치성고혈압적료효급기궤제탐토.방법 장60례CRF반난치성고혈압환자수궤분위2조.A조(HD조)응용매주3차표준혈액투석(HD)치료;B조(HDF조)행매주1차상규표준혈액투석(HD)치료화매주2차혈액투석려과(HDF)치료.비교량조환자치료전급치료후8주갑상방선소(iPTH)、혈장신소(RA)、혈관긴장소Ⅱ(Ang Ⅱ)、평균동맥압적변화.결과 B조환자iPTH、혈장신소(RA)、혈관긴장소Ⅱ(Ang Ⅱ)교A조균명현하강,평균동맥압역하강경가현저.결론 혈액투석려과능유효지청제혈장RA、AngⅡ、갑상방선소(iPTH)등중분자독소,치료난치성고혈압효과우우혈액투석,치득림상추엄.
Objective To compare the HDF with standard blood dialysis treatment of chronic renal failure (CRF) in patients with refractory hypertension and its mechanism.ethod sixty cases of CRF in patients with refractory hypertension were randomly divided nto 2 groups.A group(HD),3 times a week application standard hemodialysis treatment:B roup (HDF),1st week trip conventional HD treatment and 2 times per week HDF treatment.omparing the two groups of patients before treatment and after treatment for 8 weeks arathyroid hormone(iPTH),plasma renin(RA),angiotensin II(Ang II),mean arterial pressure.Result B patients iPTH,plasma renin(RA),angiotensin II(Ang II)than the A group weresignificantlY decreased mean arterial blood pressure also dropped significantly more.Conclusion Hemodiafiltration can effectively remove plasma PA,Ang II,parathyroid hormone (iPTH),and other elements of toxins,the treatment of refractory high blood pressure is more effective than hemodialysis,worthy to be popularized.
