中国医师进修杂志
中國醫師進脩雜誌
중국의사진수잡지
CHINESE JOURNAL OF POSTGRADUATES OF MEDICINE
2011年
13期
30-32
,共3页
脑炎,病毒性%预后%危险因素%回归分析
腦炎,病毒性%預後%危險因素%迴歸分析
뇌염,병독성%예후%위험인소%회귀분석
Encephalitis,viral%Prognosis%Risk factors%Regression analysis
目的 探讨影响病毒性脑炎近期预后的相关危险因素.方法 回顾性分析124例病毒性脑炎患者的临床资料,应用格拉斯哥预后量表(COS)分级将患者分为预后良好组(89例)和预后不良组(35例).并选取14个危险因素进行Logistic回归分析.结果 单因素分析表明,抽搐持续时间、意识障碍、局灶性神经功能缺损,头颅MRI异常、脑电图重度异常与病毒性脑炎近期预后有显著相关性(P＜0.05);而年龄、性别、精神行为异常、脑膜刺激征、脑脊液(CSF)压力、CSF白细胞数、CSF蛋白、外周血白细胞计数、头颅CT异常与病毒性脑炎近期预后无显著相关性(P＞0.05).多因素分析表明,抽搐持续时间(OR=2.877,P=0.005)和头颅MRI异常(OR=16.582,P=0.008)为影响病毒性脑炎近期预后的独立危险因素.结论 病毒性脑炎的预后是多因素共同作用的结果,头颅MRI异常和抽搐持续时间是影响病毒性脑炎近期预后的独立危险因素.
目的 探討影響病毒性腦炎近期預後的相關危險因素.方法 迴顧性分析124例病毒性腦炎患者的臨床資料,應用格拉斯哥預後量錶(COS)分級將患者分為預後良好組(89例)和預後不良組(35例).併選取14箇危險因素進行Logistic迴歸分析.結果 單因素分析錶明,抽搐持續時間、意識障礙、跼竈性神經功能缺損,頭顱MRI異常、腦電圖重度異常與病毒性腦炎近期預後有顯著相關性(P＜0.05);而年齡、性彆、精神行為異常、腦膜刺激徵、腦脊液(CSF)壓力、CSF白細胞數、CSF蛋白、外週血白細胞計數、頭顱CT異常與病毒性腦炎近期預後無顯著相關性(P＞0.05).多因素分析錶明,抽搐持續時間(OR=2.877,P=0.005)和頭顱MRI異常(OR=16.582,P=0.008)為影響病毒性腦炎近期預後的獨立危險因素.結論 病毒性腦炎的預後是多因素共同作用的結果,頭顱MRI異常和抽搐持續時間是影響病毒性腦炎近期預後的獨立危險因素.
목적 탐토영향병독성뇌염근기예후적상관위험인소.방법 회고성분석124례병독성뇌염환자적림상자료,응용격랍사가예후량표(COS)분급장환자분위예후량호조(89례)화예후불량조(35례).병선취14개위험인소진행Logistic회귀분석.결과 단인소분석표명,추휵지속시간、의식장애、국조성신경공능결손,두로MRI이상、뇌전도중도이상여병독성뇌염근기예후유현저상관성(P＜0.05);이년령、성별、정신행위이상、뇌막자격정、뇌척액(CSF)압력、CSF백세포수、CSF단백、외주혈백세포계수、두로CT이상여병독성뇌염근기예후무현저상관성(P＞0.05).다인소분석표명,추휵지속시간(OR=2.877,P=0.005)화두로MRI이상(OR=16.582,P=0.008)위영향병독성뇌염근기예후적독립위험인소.결론 병독성뇌염적예후시다인소공동작용적결과,두로MRI이상화추휵지속시간시영향병독성뇌염근기예후적독립위험인소.
Objective To investigate the risk factors of short-term prognosis in patients with viral encephalitis. Methods Clinical data of 124 patients with viral encephalitis were analyzed retrospectively. All patients were divided into good prognosis group and poor prognosis group according to the Glasgow outcome scale. Fourteen related risk factors were chosen and multifactor Logistic regression analysis was made. Results Univariate analysis showed, the duration of seizure, consciousness disorder, deficiency of cranial nerves, severe abnormal electroencephalogram and abnormal cranial MRI had significant correlation with short-term prognosis (P＜0.05), but age, sex,behavior disorder, meningeal irritation sign, pressure of cerebrospinal fluid (CSF), leukocyte number of CSF, protein level of CSF, peripheral white blood cell, and abnormal cranial CT had no correlation with short-term prognosis (P ＞0.05). Multivariate analysis showed that the abnormal of cranial MRI and the duration of seizure were the independent risk factors of short-term prognosis. Conclusions The short-term prognosis of viral encephalitis relates with many factors. The abnormal cranial MRI and the duration of seizure are the important related risk factors.
