CAJ | 학술논문

目的分析A型肉毒毒素治疗发作期偏头痛的临床效果.方法 60例偏头痛患者被随机分为对照组(M)和治疗组(C),对照组给予尼莫地平片,治疗组给予A型肉毒毒素,30 d后观察临床疗效.结果对照组和治疗组的总有效率分别为76.7%和96.7%(P＜0.05);治疗组疼痛发作时间减少和伴随症状(眩晕、耳鸣、异物感)人数明显减少,与对照组差异有极显著性(P＜0.01).结论 A型肉毒毒素治疗偏头痛发作期有明显的临床疗效.
목적 분석A형육독독소치료발작기편두통적림상효과.방법 60례편두통환자피수궤분위대조조(M)화치료조(C),대조조급여니막지평편,치료조급여A형육독독소,30 d후관찰림상료효.결과 대조조화치료조적총유효솔분별위76.7%화96.7%(P＜0.05);치료조동통발작시간감소화반수증상(현훈、이명、이물감)인수명현감소,여대조조차이유겁현저성(P＜0.01).결론 A형육독독소치료편두통발작기유명현적림상료효.
Objective To observe the clinical effects of BTX-A on the period of onset of migraine.Methods Sixty patients with migraine attacks were randomly divided into treatment group(C)and control group (M).Patients in control group(M)were given nimodipine tablets,and patients in treatment group were given BTX-A.changes of clinical effect were observed after 30 days.Results Total effeclive rates in control group and treatment group were 76.7% and 96.7%,respectively(P＜0.05).The pain onset time reduced and the numbers of the cases with the simultaneous phenomena of dizziness,tinnitus and foreign body sensation decreased significantly(P＜0.01).Conclusion BTX-A has a significant therapeutic effect on the period of onset of migraine.