CAJ | 학술논문

目的探讨采用抗生素骨水泥占位器二期翻修治疗人工髋关节感染的疗效.方法自2004年5月至2010年12月,15例初次髋关节置换术后感染患者行二期翻修手术.一期手术中取出假体并彻底清创,放置抗生素骨水泥占位器,术后静脉输入抗生素3周后改为口服抗生素4周.二期置换手术于4～6个月后进行.其中髋关节功能采用Harris评分进行评价.结果 15例患者均获得随访,随访时间8～36个月.所有患者伤口均一期愈合,感染无复发.术后Harris评分较术前明显提高(85±8 vs 42±7,P＜0.05).结论彻底清创、应用抗生素骨水泥占位器能够有效控制感染复发和提高二期置换手术效果.
목적 탐토채용항생소골수니점위기이기번수치료인공관관절감염적료효.방법 자2004년5월지2010년12월,15례초차관관절치환술후감염환자행이기번수수술.일기수술중취출가체병철저청창,방치항생소골수니점위기,술후정맥수입항생소3주후개위구복항생소4주.이기치환수술우4～6개월후진행.기중관관절공능채용Harris평분진행평개.결과 15례환자균획득수방,수방시간8～36개월.소유환자상구균일기유합,감염무복발.술후Harris평분교술전명현제고(85±8 vs 42±7,P＜0.05).결론 철저청창、응용항생소골수니점위기능구유효공제감염복발화제고이기치환수술효과.
Objective To investigate the efficacy of antibiotic bone cement spacer on postoperative infection of artificial hip arthroplasty.Methods From May 2004 to December 2010,15 patients suffered from infection after primary hip arthroplasty were performed with revision surgery.First step to remove the prosthesis and do debridement,then antibiotic bone cement spacer was placed in the joint.After the operation patients were treated with intravenous antibiotics for 3 weeks,then changed to oral antibiotics for 4 weeks.Second step the revision surgery was done after 4-6 months.Harris hip score was used for evaluation.Results Fifteen patients were followed up for 8 to 36 months.The wounds healed well of all patients and without infection recurrence.Postoperative Harris hip score(85±8) improved significantly compared with the preoperative score(42±7) (P ＜ 0.05).Conclusions The debridement and using the antibiotic bone cement spacer was able to effectively control the infection recurrence and improve the efficacy of the revision surgery on infection in artificial hip arthroplasty.