CAJ | 학술논문

目的探讨绝经后女性2型糖尿病患者骨密度与大血管并发症的相关性.方法对137例符合1999年世界卫生组织(WHO)糖尿病诊断标准的绝经后女性2型糖尿病住院患者,应用骨密度仪测定骨密度和T值,根据有无大血管并发症分2组,比较骨密度和T值.应用多因素非条件Logistic回归分析骨质疏松与大血管并发症的相关性.结果绝经后女性2型糖尿病合并大血管并发症组的骨密度、T值显著低于不伴有大血管并发症组(P＜0.01～0.05),调整了年龄、血压、血脂、体重指数、糖尿病病程、绝经时间后,经多因素非条件Logistic回归分析显示骨质疏松与大血管并发症仍存在显著的相关性(OR=4.473,95%CI:1.770～11.300).结论绝经后女性2型糖尿病患者骨密度的降低可能与大血管并发症的发生、发展有关.
목적 탐토절경후녀성2형당뇨병환자골밀도여대혈관병발증적상관성.방법 대137례부합1999년세계위생조직(WHO)당뇨병진단표준적절경후녀성2형당뇨병주원환자,응용골밀도의측정골밀도화T치,근거유무대혈관병발증분2조,비교골밀도화T치.응용다인소비조건Logistic회귀분석골질소송여대혈관병발증적상관성.결과 절경후녀성2형당뇨병합병대혈관병발증조적골밀도、T치현저저우불반유대혈관병발증조(P＜0.01～0.05),조정료년령、혈압、혈지、체중지수、당뇨병병정、절경시간후,경다인소비조건Logistic회귀분석현시골질소송여대혈관병발증잉존재현저적상관성(OR=4.473,95%CI:1.770～11.300).결론 절경후녀성2형당뇨병환자골밀도적강저가능여대혈관병발증적발생、발전유관.
Objective To assess the association between bone mineral density and macrovascular complications in postmenopausal women with type 2 diabetes. Methods To measure bone mineral density and T score of 137 postmenopausal women with type 2 diabetes, we divided these women into two groups according to whether they have macrovascular complications or not, and analysed the association between osteoporosis and macrovascular complications. Results Bone mineral density,T score of patients with macrovascular complications were much lower than those of patients without it. Osteoporosis was related to macrovascular complications by logistic regression analysis, regardless of age, pressure, triglyceride, body mass index, the duration of diabetes,and menopause time. Conclusion Decrease of bone mineral density in postmenopausal women with type 2 diabetes may be related to the development of macrovascular complications.