CAJ | 학술논문

原发性甲状腺功能减退症(甲减)患者血中甲状腺激素水平降低,由于负反馈作用减弱使垂体增大,单纯影像学检查易与垂体瘤混淆；同时甲减合并肌酸激酶显著升高的病例也不少见,可能会被误诊为肌炎.本文介绍1例原发性甲减合并明显垂体增生、肌酸激酶升高患者的诊治过程,以引起对甲减非特异临床表现的重视,进行正确的治疗.
원발성갑상선공능감퇴증(갑감)환자혈중갑상선격소수평강저,유우부반궤작용감약사수체증대,단순영상학검사역여수체류혼효；동시갑감합병기산격매현저승고적병례야불소견,가능회피오진위기염.본문개소1례원발성갑감합병명현수체증생、기산격매승고환자적진치과정,이인기대갑감비특이림상표현적중시,진행정학적치료.
Pituitary hyperplasia may be found in patients with primary hypothyroidism as the decreased thyroid hormone level attenuates negative feedback effect.Sometimes the enlarged pituitary may be misdiagnosed as a pituitary tumor.Patients with long term untreated hypothyroidism often have extremely high level of serum creatine kinase and thus may be misdiagnosed as suffering from myositis.In order to increase the awareness of the nonspecific symptoms of primary hypothyroidism,this article introduces the diagnosis and treatment of a patient with primary hypothyroidism with raised serum creatine kinase level and pituitary hyperplasia.