中国实用医刊
中國實用醫刊
중국실용의간
CENTRAL PLAINS MEDICAL JOURNAL
2012年
13期
3-4
,共2页
昏迷患者%血清心肌酶%肌钙蛋白
昏迷患者%血清心肌酶%肌鈣蛋白
혼미환자%혈청심기매%기개단백
Patients with coma%Serum myocardial enzymes%Troponin
目的 通过观察昏迷患者的血清心肌酶及肌钙蛋白(cTnI)的动态变化,估计病情严重程度及预后,了解cTnI的临床意义.方法 选择60例ICU内科不同程度昏迷患者,通过测定入院后第2、5、7天天门冬氨酸氨基转移酶(AST)、肌酸激酸(CK)、肌酸激酶同工酶(CK-MB)、乳酸脱氢酶(LDH)及cTnI的动态变化,比较心肌酶谱的异常情况.结果 昏迷患者急性期心肌酶均有不同程度的异常发生率,且与昏迷程度呈正相关性,而CK-MB及cTnI对提示心脑综合征的发生有更大临床意义.结论 昏迷患者中血清心肌酶谱异常发生率与昏迷病因无明显相关,与昏迷程度有相关性,且AST、CK、CK-MB、LDH及cTnI临床意义有区别,合并脑心综合征(心电图有改变)者CK-MB和cTnI变化更显著,无明显心电图改变者CK-MB和cTnI变化不明显.
目的 通過觀察昏迷患者的血清心肌酶及肌鈣蛋白(cTnI)的動態變化,估計病情嚴重程度及預後,瞭解cTnI的臨床意義.方法 選擇60例ICU內科不同程度昏迷患者,通過測定入院後第2、5、7天天門鼕氨痠氨基轉移酶(AST)、肌痠激痠(CK)、肌痠激酶同工酶(CK-MB)、乳痠脫氫酶(LDH)及cTnI的動態變化,比較心肌酶譜的異常情況.結果 昏迷患者急性期心肌酶均有不同程度的異常髮生率,且與昏迷程度呈正相關性,而CK-MB及cTnI對提示心腦綜閤徵的髮生有更大臨床意義.結論 昏迷患者中血清心肌酶譜異常髮生率與昏迷病因無明顯相關,與昏迷程度有相關性,且AST、CK、CK-MB、LDH及cTnI臨床意義有區彆,閤併腦心綜閤徵(心電圖有改變)者CK-MB和cTnI變化更顯著,無明顯心電圖改變者CK-MB和cTnI變化不明顯.
목적 통과관찰혼미환자적혈청심기매급기개단백(cTnI)적동태변화,고계병정엄중정도급예후,료해cTnI적림상의의.방법 선택60례ICU내과불동정도혼미환자,통과측정입원후제2、5、7천천문동안산안기전이매(AST)、기산격산(CK)、기산격매동공매(CK-MB)、유산탈경매(LDH)급cTnI적동태변화,비교심기매보적이상정황.결과 혼미환자급성기심기매균유불동정도적이상발생솔,차여혼미정도정정상관성,이CK-MB급cTnI대제시심뇌종합정적발생유경대림상의의.결론 혼미환자중혈청심기매보이상발생솔여혼미병인무명현상관,여혼미정도유상관성,차AST、CK、CK-MB、LDH급cTnI림상의의유구별,합병뇌심종합정(심전도유개변)자CK-MB화cTnI변화경현저,무명현심전도개변자CK-MB화cTnI변화불명현.
[Objective] By observing the dynamic change of serum myocardial enzymes and troponin in patients with coma,to estimate the severity and prognosis of the disease,and to understand the clinical significance of cTnI.[Methods] By measuring the dynamic change of AST,CK,CK-MB,LDH,and cTnI in 60 patients with varying degrees of coma in ICU at the 2nd,5th,7th day after admission,to compare the myocardial enzyme spectrum abnormalities.[Results] The myocardial enzymes had different degrees of abnormal incidence in patients with coma at acute stage,and was positively correlated with coma degree,while CK-MB and cTnI had a greater clinical significance in estimating the incidence of the cardio-cerebral syndrome.[Conclusions] The abnormal incidence of serum myocardial enzymes in patients with coma is not correlated with the unconscious causes,while is correlated with the coma degree,and the clinical significance of AST,CK,CK-MB,LDH and cTnI are different,there are more significant changes of CK-MB and cTnI in patients with cardio-cerebral syndrome(ECG changes),but has no significant change in patients with no significant ECG changes.
