CAJ | 학술논문

目的探讨静脉淤血皮瓣微循环的变化规律.方法选择兔耳建立静脉淤血的皮瓣模型,采用活体微循环动态观察的方法,观察观察静脉淤血组织内部微循环的变化.结果皮瓣静脉淤血后,其原有微血管的数目逐渐减少,微血流的速度逐渐减慢,红细胞聚集和白色微血栓形成的情况逐渐加重,72 h皮瓣原有的微循环系统基本衰竭.静脉淤血后36 h,可以观察到有新生微血管的出现;48 h,可以观察到较清晰的新生微血管.观察到新生微血管的淤血组织最终成活,而未观察到新生微血管的淤血组织最终坏死.结论对于发生静脉淤血的皮瓣,如果不及时解除淤血的原因,其原有的微循环系统呈不可逆的进行性恶化,而微血管的新生对淤血组织的成活起了重要作用.
목적 탐토정맥어혈피판미순배적변화규률.방법 선택토이건립정맥어혈적피판모형,채용활체미순배동태관찰적방법,관찰관찰정맥어혈조직내부미순배적변화.결과 피판정맥어혈후,기원유미혈관적수목축점감소,미혈류적속도축점감만,홍세포취집화백색미혈전형성적정황축점가중,72 h피판원유적미순배계통기본쇠갈.정맥어혈후36 h,가이관찰도유신생미혈관적출현;48 h,가이관찰도교청석적신생미혈관.관찰도신생미혈관적어혈조직최종성활,이미관찰도신생미혈관적어혈조직최종배사.결론 대우발생정맥어혈적피판,여과불급시해제어혈적원인,기원유적미순배계통정불가역적진행성악화,이미혈관적신생대어혈조직적성활기료중요작용.
Objective To explore the change patterns of microcirculation in congested flap. Methods A congested flap model for long-term microeirculation observation was set up, and the mi-crocireulation of the congested tissues was observed carefully. Results Following congestion, the number of the capillaries in the congested flap were decreasing, the velocity of the bloodstreams were getting slower, and the aggregation of the red blood cells and the formation of the white thrombus were becoming more serious. About 72 hours later, the original microcirculation system of the flap was nearly exhausted. About 36 hours later, the neogenetie capillaries could be observed, with clear neogenetie capillaries observed at 48 hours. The congested tissues with nascent capillaries survived, while the capillaries without nascent formation suffered from necrosis in the end. Conclusions If the cause is not removed, the microcirculation status of the congested flap would get worse irreversibly, and the nascent capillaries would play an important role in the survival of congested tissues.