上海第二医科大学学报(英文版)
上海第二醫科大學學報(英文版)
상해제이의과대학학보(영문판)
JOURNAL OF SHANGHAI SECOND MEDICAL UNIVERSITY
2003年
2期
132-135
,共4页
glycosides of radix Tripterygii long-term treatment glomerulonephritis
Objective To assess the therapeutic effects and side actions of glycoside of radix Tripterygii wilfordii in long-term treatment of a variety of glomerulonephritis. Methods 65 patients including 21,15,18 and 11 with IgA nephropathy, mesangial proliferative glomerulonephritis (MsPGN), focal segmental glomerular sclerosis (FSGS) and anaphylactoid purpura respectively, were treated with glycoside of radix Tripterygii for 12-18 months. Proteinuria and hematuria and serum soluble interleukin-2R(SIL-2R) in all patients were determined before treatment and at the end of 12-18 months. Results The results showed that 28 patients had remission, 18 improvement and 19 no effects. The total effective rate was 70%. There were signifi-cant decreases in serum SIL-2R after treatment. Conclusion Long-term treatment with glycoside of radix Tripterygii is effective, resulting in less side actions and decreased recurrent rates of IgAN、MsPGN、FSGS and anaphylactoid purpura.
