CAJ | 학술논문

背景青光眼是导致不可逆盲的常见病因之一,且青光眼的患病类型在全球不同地区分布有所差异.目的了解新疆库车县成年维吾尔族农民青光眼患病率及常见的患病类型,为该地区和该民族青光眼的防治提供依据.方法2009年3～4月新疆医科大学第一附属医院眼科采用单纯随机整群抽样的方法对新疆库车县14个村4191名40岁以上成年维吾尔族农民进行青光眼调查,受检者按年龄分为40～49、50～59、60～69组和≥70岁组.调查事先经过新疆医科大学伦理委员会审批,所有受检者受试前均签署知情同意书后方进行相关检查.所有检查者均经过调查标准化培训.调查内容包括病史、常规眼部检查及前房深度、房角镜、眼底检查,必要时行暗室俯卧试验、散瞳实验明确青光眼患病类型.周边前房深度诊断按照van Herick标准,前房角关闭的分级标准采用Scheie分级法.结果检录的4873名受检者中4191人完成眼部检查及相关的青光眼检查,受检率为86.0%,受检者依从性好.青光眼的患病率为3.79%,其中原发性闭角型青光眼(PACG)、原发性开角型青光眼(POAG)及继发性青光眼的患病率分别为2.22%、0.26%及1.31%,差异有统计学意义(P<0.05).各型青光眼患病率均随年龄的增长而增加,不同年龄组间患病率的差异有统计学意义(χ2=116.69,P<0.05),男性患者的患病率明显高于女性(χ2=7.34,P<0.05).受检确诊的青光眼患者中19.75%为双眼盲,其中有25.30%的患者行抗青光服手术,不同年龄组视力的差异有统计学意义(χ2=37.69,P<0.05).结论新疆库车县成年维吾尔族农民青光眼患病率高于大部分国内及国外调查结果.PACG仍为最常见的青光眼患病类型.
배경 청광안시도치불가역맹적상견병인지일,차청광안적환병류형재전구불동지구분포유소차이.목적 료해신강고차현성년유오이족농민청광안환병솔급상견적환병류형,위해지구화해민족청광안적방치제공의거.방법2009년3～4월신강의과대학제일부속의원안과채용단순수궤정군추양적방법대신강고차현14개촌4191명40세이상성년유오이족농민진행청광안조사,수검자안년령분위40～49、50～59、60～69조화≥70세조.조사사선경과신강의과대학윤리위원회심비,소유수검자수시전균첨서지정동의서후방진행상관검사.소유검사자균경과조사표준화배훈.조사내용포괄병사、상규안부검사급전방심도、방각경、안저검사,필요시행암실부와시험、산동실험명학청광안환병류형.주변전방심도진단안조van Herick표준,전방각관폐적분급표준채용Scheie분급법.결과 검록적4873명수검자중4191인완성안부검사급상관적청광안검사,수검솔위86.0%,수검자의종성호.청광안적환병솔위3.79%,기중원발성폐각형청광안(PACG)、원발성개각형청광안(POAG)급계발성청광안적환병솔분별위2.22%、0.26%급1.31%,차이유통계학의의(P<0.05).각형청광안환병솔균수년령적증장이증가,불동년령조간환병솔적차이유통계학의의(χ2=116.69,P<0.05),남성환자적환병솔명현고우녀성(χ2=7.34,P<0.05).수검학진적청광안환자중19.75%위쌍안맹,기중유25.30%적환자행항청광복수술,불동년령조시력적차이유통계학의의(χ2=37.69,P<0.05).결론 신강고차현성년유오이족농민청광안환병솔고우대부분국내급국외조사결과.PACG잉위최상견적청광안환병류형.
Background Glaucoma is one of the leading causes of blindness worldwide;while the different types of glaucoma is vary from different region. Objective Present study was to survey the prevalence and types of glaucoma among peasants of Uigur adults in Kuche county and offer the basis for the prevent and treatment of glaucoma in Uigur nationanlity. Methods 4191 Uigur peasants aged 40 years or above were collected in Kuche county for the survey of prevalence and types of glaucoma by randomized cluster sampling in March and April of 2009. The subjects were grouped into 40-,50-,60- and ≥70 years groups according to the distribution of age. The disease history of glaucoma, regular eye examination, funds examination and measurement of the anterior chamber depth, gonioscope were performed in the all subjects. Darkroom prone test and mydriasis test were carried out in suspicious glaucomous patients. The depth of periphery anterior chamber was assessed based on van Herick' s criteria, and the width of chamber angle was graded based on Scheie' s method. The standardized training was performed. This survey approved by Xinjiang Medical Ethics Committee, all subjects signed the informed consent before the examination. Results 4191 of 4873 subjects finished all the examinations with the response rate 86%. All the subjects showed a good compliance. The prevalence of glaucoma was 3. 79% , and the prevalence of primary angle-closed glaucoma(PACG) .primary angle-open glaucoma (PAOG) and secondary glaucoma was 2.22% ,0.26% and 1. 31% respectively, showing a significant difference among the different types of glaucoma( P<0. 05). The prevalence of glaucoma was elevated with aging (χ2 - 116. 69 ,P<0. 05) and presented a high rate in male subjects compared with female ones(χ2 = 7. 34, P<0. 05 ). Bilateral blindness was found in 19.75% glaucoma peasants, in which 25.3% glaucoma peasants received anti-glaucoma surgery. The distribution of visual acuity of patients was of significant difference among different age groups(χ2 = 37. 69 ,P<0. 05 ) . Conclusions The prevalence of the glaucoma among Uigur peasants in Kuche county was higher than most area no matter inland or overseas. PACG still is the common type in those people.