CAJ | 학술논문

我们前期从红花锦鸡儿(Caragana rosea)中发现两个具有抗HIV活性成分seirpusin A和B(含量仅约百万分之一),为了寻找富含该化合物的新的植物资源,我们对产于黑龙江省的荆三棱(Scirpus yagara)的化学成分进行了研究,从其乙醇提取物的乙酸乙酯萃取部位分离到6个化合物.通过1H NMR分析及与对照品TLC比较,分别鉴定为:白桦醇(1),对羟基桂皮酸(2),scirpusin A(3),白藜芦醇(4),piceatannol(5)及scirpusin B(6).其中,化合物scirpusin A和B,在该植物中含量丰富(含量分别为0.017%和0.013%).
아문전기종홍화금계인(Caragana rosea)중발현량개구유항HIV활성성분seirpusin A화B(함량부약백만분지일),위료심조부함해화합물적신적식물자원,아문대산우흑룡강성적형삼릉(Scirpus yagara)적화학성분진행료연구,종기을순제취물적을산을지췌취부위분리도6개화합물.통과1H NMR분석급여대조품TLC비교,분별감정위:백화순(1),대간기계피산(2),scirpusin A(3),백려호순(4),piceatannol(5)급scirpusin B(6).기중,화합물scirpusin A화B,재해식물중함량봉부(함량분별위0.017%화0.013%).
Scirpusin A and B were identified as active agents against HIV from Caragana rosea in our previous study (yield 1×10-4%).In order to find new rich resource for the two compounds,we conducted a chemical investigation of rhizome of Scirpus yagara Owhi growing in Heilongjiang Province.Six compounds were isolated from the EtOAc fraction of this plant.On the basis of1H NMR as well as by comparison with authentic samples.they were identified as betulin (1),p-hydroxy cinnamic acid(2),scirpusin A(3),resvemtrol(4),piceatannol(5),and scirpusin B(6) respective-ly.Scirpusin A and B were proved to be rich in this plant(yield 0.017%and 0.013%).