中国综合临床
中國綜閤臨床
중국종합림상
CLINICAL MEDICINE OF CHINA
2012年
5期
491-493
,共3页
特发性肺栓塞%高密度脂蛋白胆固醇%总胆固醇%低密度脂蛋白胆固醇
特髮性肺栓塞%高密度脂蛋白膽固醇%總膽固醇%低密度脂蛋白膽固醇
특발성폐전새%고밀도지단백담고순%총담고순%저밀도지단백담고순
Idiopathic pulmonary embolism%High-density lipoprotein cholesterol%Total cholesterol%Low-density lipoprotein cholesterol
目的 探讨高密度脂蛋白胆固醇( HDL-C)与特发性肺栓塞之间的关系.方法 收集我院2005年1月至2011年3月确诊的34例特发性肺栓塞患者(PE组)临床资料,选择同时期性别、年龄、基础疾病相匹配的我院体检中心健康体检者109名为对照组.PE组和对照组均空腹10h后次日7:00抽取肘部静脉血,检测血总胆固醇(TC)、HDL-C、低密度脂蛋白胆固醇(LDL-C).结果 PE组与对照组在HDL-C比较中差异有统计学意义[分别为:(1.10±0.28)、(1.49±0.35) mmol/L,t=- 5.427、P<D.05],而两组在TC、LDL-C差异均无统计学意义(P均>0.05).特发性肺栓塞与HDL-C存在一定联系(r =0.284,P<0.05).结论 TC与LDL-C与特发性肺栓塞可能无关,而HDL-C与特发性肺栓塞存在一定关系.
目的 探討高密度脂蛋白膽固醇( HDL-C)與特髮性肺栓塞之間的關繫.方法 收集我院2005年1月至2011年3月確診的34例特髮性肺栓塞患者(PE組)臨床資料,選擇同時期性彆、年齡、基礎疾病相匹配的我院體檢中心健康體檢者109名為對照組.PE組和對照組均空腹10h後次日7:00抽取肘部靜脈血,檢測血總膽固醇(TC)、HDL-C、低密度脂蛋白膽固醇(LDL-C).結果 PE組與對照組在HDL-C比較中差異有統計學意義[分彆為:(1.10±0.28)、(1.49±0.35) mmol/L,t=- 5.427、P<D.05],而兩組在TC、LDL-C差異均無統計學意義(P均>0.05).特髮性肺栓塞與HDL-C存在一定聯繫(r =0.284,P<0.05).結論 TC與LDL-C與特髮性肺栓塞可能無關,而HDL-C與特髮性肺栓塞存在一定關繫.
목적 탐토고밀도지단백담고순( HDL-C)여특발성폐전새지간적관계.방법 수집아원2005년1월지2011년3월학진적34례특발성폐전새환자(PE조)림상자료,선택동시기성별、년령、기출질병상필배적아원체검중심건강체검자109명위대조조.PE조화대조조균공복10h후차일7:00추취주부정맥혈,검측혈총담고순(TC)、HDL-C、저밀도지단백담고순(LDL-C).결과 PE조여대조조재HDL-C비교중차이유통계학의의[분별위:(1.10±0.28)、(1.49±0.35) mmol/L,t=- 5.427、P<D.05],이량조재TC、LDL-C차이균무통계학의의(P균>0.05).특발성폐전새여HDL-C존재일정련계(r =0.284,P<0.05).결론 TC여LDL-C여특발성폐전새가능무관,이HDL-C여특발성폐전새존재일정관계.
Objective To investigate the relationship between high-density lipoprotein cholesterol (HDL-C) and idiopathic pulmonary embolism.Methods Clinical data of 34 patients with idiopathic pulmonary embolism from January 2005 to March 2011 were enrolled and healthy people with gender,age and basic diseasematched at the same period were selected as control.The venous blood samples of all the subjects were taken at 7:00 am after 10 hours of fasting and analyzed for total cholesterol (TC),lower-density lipoprotein cholesterol (LDL-C) and high-density lipoprotein cholesterol (HDL-C).Results Compared with healthy people,patients had reduced HDL-C level with a statistical significance ( ( 1.10 ± 0.28 ) mmol/L vs ( 1.49 ± 0.35 ) mmol/L,t =- 5.427,P < 0.05 ).However,no statistically significant differences were found in the levels of TC and LDL- C (P > 0.05 ).HDL-C was correlated with idiopathic pulmonary embolism( r =0.284,P < 0.05 ).Conclusion The levels of HDL-C,but not TC or LDL-C,might be associated with the idiopathic pulmonary embolism.