CAJ | 학술논문

目的探讨强脉冲光联合调Q激光疗法对面部色素增生性皮肤病的疗效及安全性.方法根据患者面部色素性疾病的特点,对225例Fitzpatrick Ⅲ、Ⅳ型皮肤的色素细胞增生性皮肤病患者,采用560 nm强脉冲光联合凋Q 532 nm激光治疗.首先使用560 nm强脉冲光,能量密度30～40 J/cm~2的光子嫩肤治疗,每月1次,3个月后观察疗效.对于改善不显著的脂溢性角化斑、咖啡斑及眼睑、口唇周围残留的雀斑等.再使用调Q 532 nm激光,施行局部针对性治疗,能量密度70 J/cm~2.于激光治疗后2个月,对皮损的改善和满意度进行评估并记录不良反应.结果 90%患者的雀斑、咖啡斑、脂溢性角化斑的色素均有50%～70%不同程度的消退,同时毛细血管扩张、毛孔粗大、细小皱纹均达到了60%以上的程度的改善.主要并发症为暂时性红斑和水疱.结论 560 nm强脉冲光联合调Q激光治疗面部色素增生性皮肤病安全有效.同时能有效改善肤质.
목적 탐토강맥충광연합조Q격광요법대면부색소증생성피부병적료효급안전성.방법 근거환자면부색소성질병적특점,대225례Fitzpatrick Ⅲ、Ⅳ형피부적색소세포증생성피부병환자,채용560 nm강맥충광연합조Q 532 nm격광치료.수선사용560 nm강맥충광,능량밀도30～40 J/cm~2적광자눈부치료,매월1차,3개월후관찰료효.대우개선불현저적지일성각화반、가배반급안검、구진주위잔류적작반등.재사용조Q 532 nm격광,시행국부침대성치료,능량밀도70 J/cm~2.우격광치료후2개월,대피손적개선화만의도진행평고병기록불량반응.결과 90%환자적작반、가배반、지일성각화반적색소균유50%～70%불동정도적소퇴,동시모세혈관확장、모공조대、세소추문균체도료60%이상적정도적개선.주요병발증위잠시성홍반화수포.결론 560 nm강맥충광연합조Q격광치료면부색소증생성피부병안전유효.동시능유효개선부질.
Objective To observe the effect of non-ablative treatment combined intense pulse light (IPL) and Q switched Nd :YAG laser on hyperpigmented skin diseases. Methods Total 250 cases of Fitzpatrick skin types Ⅲ and Ⅳ with hyperpigmented skin disorders received 4 treatments with combined 560nm IPI. and 532 nm Q switched Nd :YAG laser. The interval between two treat-ments was I month. After 3 months the effect of IPL was observed. If it was not good, we used the Q switched Nd :YAG laser. Efficacy and adverse effects were evaluated 3-6 months after the final treat-ment. Results 3-6 months after the last treatment, 50%-70% of patients had their telangiectasia, enlarged pores, hyperpigmentation and wrinking of facial photoaging improved. The degree of im-provement was more than 60 %. Common side effects were minor blistering and erythema. Conclusion Combined IPI. and Q switched Nd :YAG laser treatment is an idea non-ablative therapy for telangi-ectasia, enlarged pores, hyperpigmentation and wrinking of facial photoaging in Fitzpatrick skin types Ⅲ and Ⅳ in Asian.