中国基层医药
中國基層醫藥
중국기층의약
CHINESE JOURNAL OF PRIMARY MEDICINE AND PHARMACY
2008年
5期
707-708
,共2页
疱疹,带状%复方甘草酸苷%泛昔洛韦%药物疗法%联合
皰疹,帶狀%複方甘草痠苷%汎昔洛韋%藥物療法%聯閤
포진,대상%복방감초산감%범석락위%약물요법%연합
Herpes zoster%Compound glycyrrhiz%Fameiclovir%Drug therapy%combiation
目的 观察复方甘草酸苷联合泛昔洛韦治疗带状疱疹的有效性和安全性.方法 将98例带状疱疹患者随机分成两组.治疗组50例,给予复方甘草酸苷联合泛昔洛韦治疗;对照组48例,给予泛昔洛韦治疗,疗程均1周,用药10 d后观察比较两组止疱、结痂、止痛和痊愈的时间及后遗神经痛发生率.结果 治疗组与对照组相比,在止疱[(2.38±0.76)d,(2.97±0.89)d]、结痂[(5.15±1.42)d,(6.91±1.97)d]、止痛[(4.06±1.34)d,(6.05±1.83)d]和痊愈时间[(7.32±2.21)d,(9.86±2.77)d]方面差异有统计学意义(均P<0.05),后遗神经痛发生率两组差异无统计学意义(2%,4.2%)(P0.05).结论 复方甘草酸苷联合泛昔洛韦治疗带状疱疹疗效明显优于单用泛昔洛韦.
目的 觀察複方甘草痠苷聯閤汎昔洛韋治療帶狀皰疹的有效性和安全性.方法 將98例帶狀皰疹患者隨機分成兩組.治療組50例,給予複方甘草痠苷聯閤汎昔洛韋治療;對照組48例,給予汎昔洛韋治療,療程均1週,用藥10 d後觀察比較兩組止皰、結痂、止痛和痊愈的時間及後遺神經痛髮生率.結果 治療組與對照組相比,在止皰[(2.38±0.76)d,(2.97±0.89)d]、結痂[(5.15±1.42)d,(6.91±1.97)d]、止痛[(4.06±1.34)d,(6.05±1.83)d]和痊愈時間[(7.32±2.21)d,(9.86±2.77)d]方麵差異有統計學意義(均P<0.05),後遺神經痛髮生率兩組差異無統計學意義(2%,4.2%)(P0.05).結論 複方甘草痠苷聯閤汎昔洛韋治療帶狀皰疹療效明顯優于單用汎昔洛韋.
목적 관찰복방감초산감연합범석락위치료대상포진적유효성화안전성.방법 장98례대상포진환자수궤분성량조.치료조50례,급여복방감초산감연합범석락위치료;대조조48례,급여범석락위치료,료정균1주,용약10 d후관찰비교량조지포、결가、지통화전유적시간급후유신경통발생솔.결과 치료조여대조조상비,재지포[(2.38±0.76)d,(2.97±0.89)d]、결가[(5.15±1.42)d,(6.91±1.97)d]、지통[(4.06±1.34)d,(6.05±1.83)d]화전유시간[(7.32±2.21)d,(9.86±2.77)d]방면차이유통계학의의(균P<0.05),후유신경통발생솔량조차이무통계학의의(2%,4.2%)(P0.05).결론 복방감초산감연합범석락위치료대상포진료효명현우우단용범석락위.
Objective To observe the efficacy and safety of compound glycyrrhizin and famciclovir in the treatment of herpes zoster. Methods 98 patients with herpes zoster were randomly divided into 2 groups. The treatment group were administrated with compound glycyrrhizin for a week. The control group were administrated with famciclovir for a week. The time of blister stop, crust formation, pain disappearance and cure was observed after 10 days. The rate of postherpetic neuralgia was observed too. Results The difference was significant between treatment group and control group in the time of blister stop [(2.38±0.76)d,(2.97±0.89)d], crust formation [(5.15±1.42)d, (6.91±1.97)d], pain disappearance [(4.06±1.34)d, (6.05±1.83)d] and cure [(7.32±2.21)d, (9.86±2.77)d] (all P<0.05). The difference of the rate of postherpetic neuralgia was insignificant between two groups (2%,4.2%) (P0.05). Conclusion Combined therapy of compound glycyrrhizin and famciclovir was safe and effective for the treatment of herpes zoster.
