中华内科杂志
中華內科雜誌
중화내과잡지
CHINESE JOURNAL OF INTERNAL MEDICINE
2011年
9期
747-749
,共3页
万云高%徐东%王慧娟%华琦%何士大%孔强%范振兴%刘志
萬雲高%徐東%王慧娟%華琦%何士大%孔彊%範振興%劉誌
만운고%서동%왕혜연%화기%하사대%공강%범진흥%류지
心肌梗死%脑梗死%死亡原因
心肌梗死%腦梗死%死亡原因
심기경사%뇌경사%사망원인
Myocardial infarction%Brain infarction%Cause of death
目的 分析陈旧性脑梗死对急性心肌梗死(AMI)患者住院死亡的影响.方法 回顾分析首都医科大学宣武医院2002-2009年连续住院的3572例AMI患者资料.结果 3572例AMI患者中伴陈旧性脑梗死564例(15.8%),与不伴陈旧性脑梗死相比,年龄较大[(69.4±9.9)岁比(64.2±12.9)岁,P=0.000].高血压、糖尿病、陈旧性心肌梗死、非ST段抬高性心肌梗死比例较高(71.0%比57.3%,41.0%比25.7%,12.9%比9.5%,14.9%比10.7%,P＜0.01),且住院病死率较高(16.5%比10.0%,P=0.000).陈旧性脑梗死增加住院死亡(OR 1.368,P=0.022),且独立于年龄(OR 1.048),性别(OR 1.148)、糖尿病(OR 1.337)、陈旧性心肌梗死(OR 1.294)、广泛前壁心肌梗死(OR 1.888)、介入性治疗(OR 0.506)等因素.结论 陈旧性脑梗死增加AMI患者住院死亡风险.
目的 分析陳舊性腦梗死對急性心肌梗死(AMI)患者住院死亡的影響.方法 迴顧分析首都醫科大學宣武醫院2002-2009年連續住院的3572例AMI患者資料.結果 3572例AMI患者中伴陳舊性腦梗死564例(15.8%),與不伴陳舊性腦梗死相比,年齡較大[(69.4±9.9)歲比(64.2±12.9)歲,P=0.000].高血壓、糖尿病、陳舊性心肌梗死、非ST段抬高性心肌梗死比例較高(71.0%比57.3%,41.0%比25.7%,12.9%比9.5%,14.9%比10.7%,P＜0.01),且住院病死率較高(16.5%比10.0%,P=0.000).陳舊性腦梗死增加住院死亡(OR 1.368,P=0.022),且獨立于年齡(OR 1.048),性彆(OR 1.148)、糖尿病(OR 1.337)、陳舊性心肌梗死(OR 1.294)、廣汎前壁心肌梗死(OR 1.888)、介入性治療(OR 0.506)等因素.結論 陳舊性腦梗死增加AMI患者住院死亡風險.
목적 분석진구성뇌경사대급성심기경사(AMI)환자주원사망적영향.방법 회고분석수도의과대학선무의원2002-2009년련속주원적3572례AMI환자자료.결과 3572례AMI환자중반진구성뇌경사564례(15.8%),여불반진구성뇌경사상비,년령교대[(69.4±9.9)세비(64.2±12.9)세,P=0.000].고혈압、당뇨병、진구성심기경사、비ST단태고성심기경사비례교고(71.0%비57.3%,41.0%비25.7%,12.9%비9.5%,14.9%비10.7%,P＜0.01),차주원병사솔교고(16.5%비10.0%,P=0.000).진구성뇌경사증가주원사망(OR 1.368,P=0.022),차독립우년령(OR 1.048),성별(OR 1.148)、당뇨병(OR 1.337)、진구성심기경사(OR 1.294)、엄범전벽심기경사(OR 1.888)、개입성치료(OR 0.506)등인소.결론 진구성뇌경사증가AMI환자주원사망풍험.
Objective To investigate the impact of prior cerebral infarction (PCI) on in-hospital mortality in patients with Acute Myocardial Infarction (AMI).MethodsA retrospective analysis of documents of a total of 3572 consecutive patients with AMI admitted to Xuanwu Hospital of Capital Medical University from 2002 Jan.1 to 2009 Dec.31 were performed.Results There were 564 patients ( 15.8% )with PCI.Compared with the group of without PC1,the group with PCI were substantially older[(69.4 ±9.9) vs (64.2 ± 12.9)years,P =0.000],and had a higher prevalence of hypertensive disease,diabetes mellitus,prior myocardial infarction (MI) and non-ST-segment elevation myocardial infarction(NSTEMI)( respectively,71.0% vs 57.3%; 41.0% vs 25.7%,12.9% vs 9.5%; 14.9% vs 10.7%,P ＜ 0.01 ),and a higher in-hospital mortality ( 16.5% vs 10.0%,P= 0.000).Univariate analysis demonstrated that in-hospital mortality associated with age,gender,extensive anterior MI,anterior MI,diabetes mellitus,prior cerebral infarction,prior myocardial infarction,coronary angiography and percutaneous coronary intervention.Logistic regression analysis found that risk factors were age,extensive anterior MI,anterior MI,diabetes mellitus and prior cerebral infarction,and protective factors were coronary angiography and percutanous coronary intervention.PCI was independently associated with in-hospital mortality,OR 1.368,95% CI 1.047-1.787,P = 0.022.Conclusion In patients with acute myocardial infarction,the presence of PCI increases the risk of worse in-hospital outcome.
