中华肾脏病杂志
中華腎髒病雜誌
중화신장병잡지
2008年
12期
872-877
,共6页
黄燕萍%王伟铭%裴道灵%沈平雁%俞海瑾%史浩%章倩莹%徐静%吕轶伦%樊绮诗%陈楠
黃燕萍%王偉銘%裴道靈%瀋平雁%俞海瑾%史浩%章倩瑩%徐靜%呂軼倫%樊綺詩%陳楠
황연평%왕위명%배도령%침평안%유해근%사호%장천형%서정%려질륜%번기시%진남
肾疾病%流行病学%患病率%危险因素
腎疾病%流行病學%患病率%危險因素
신질병%류행병학%환병솔%위험인소
Kidney disease%Epidemiology%Prevalence%Risk factor
目的 获取上海城市社区成年人群慢性肾脏病流行病学及其高危人群数据,有助于慢性肾脏病的早期发现、早期诊断、早期治疗及有助于国家卫生政策的制定.方法 采用多阶段整群随机抽样法对上海市长宁区江苏街道中2596名18岁以上常住居民进行问卷调查并检测肾脏损伤指标及相关危险因素,包括体格检查、尿常规+沉渣镜检、尿白蛋白,肌酐比值(ACR)、Scr、BUN、血尿酸、血糖、血胆固醇(Cho)、血三酰甘油(TG)、血红蛋白(Hb)及肾脏B超等.调查员均经过培训及接受技术指导,同时培训社区居委会有关人员,以便与居民的沟通与联络.3个月后对ACR试纸半定量检查阳性者进行复查.结果 在2554例资料完整的居民中,白蛋白尿患病率为6.3%;肾功能下降为5.8%;镜下血尿为1.2%.该人群中CKD患病率11.8%,知晓率8.2%.多因素Logistic回归提示,CKD的最强烈危险因素为高尿酸血症,其余依次为肾结石、贫血、糖尿病、腹型肥胖、高血压、年龄.结论 在上海城市社区人群中,CKD患病率为11.8%,知晓率仅为8.2%.CKD的危险因素为高尿酸血症、肾结石、贫血、糖尿病、腹型肥胖、高血压、年龄.
目的 穫取上海城市社區成年人群慢性腎髒病流行病學及其高危人群數據,有助于慢性腎髒病的早期髮現、早期診斷、早期治療及有助于國傢衛生政策的製定.方法 採用多階段整群隨機抽樣法對上海市長寧區江囌街道中2596名18歲以上常住居民進行問捲調查併檢測腎髒損傷指標及相關危險因素,包括體格檢查、尿常規+沉渣鏡檢、尿白蛋白,肌酐比值(ACR)、Scr、BUN、血尿痠、血糖、血膽固醇(Cho)、血三酰甘油(TG)、血紅蛋白(Hb)及腎髒B超等.調查員均經過培訓及接受技術指導,同時培訓社區居委會有關人員,以便與居民的溝通與聯絡.3箇月後對ACR試紙半定量檢查暘性者進行複查.結果 在2554例資料完整的居民中,白蛋白尿患病率為6.3%;腎功能下降為5.8%;鏡下血尿為1.2%.該人群中CKD患病率11.8%,知曉率8.2%.多因素Logistic迴歸提示,CKD的最彊烈危險因素為高尿痠血癥,其餘依次為腎結石、貧血、糖尿病、腹型肥胖、高血壓、年齡.結論 在上海城市社區人群中,CKD患病率為11.8%,知曉率僅為8.2%.CKD的危險因素為高尿痠血癥、腎結石、貧血、糖尿病、腹型肥胖、高血壓、年齡.
목적 획취상해성시사구성년인군만성신장병류행병학급기고위인군수거,유조우만성신장병적조기발현、조기진단、조기치료급유조우국가위생정책적제정.방법 채용다계단정군수궤추양법대상해시장저구강소가도중2596명18세이상상주거민진행문권조사병검측신장손상지표급상관위험인소,포괄체격검사、뇨상규+침사경검、뇨백단백,기항비치(ACR)、Scr、BUN、혈뇨산、혈당、혈담고순(Cho)、혈삼선감유(TG)、혈홍단백(Hb)급신장B초등.조사원균경과배훈급접수기술지도,동시배훈사구거위회유관인원,이편여거민적구통여련락.3개월후대ACR시지반정량검사양성자진행복사.결과 재2554례자료완정적거민중,백단백뇨환병솔위6.3%;신공능하강위5.8%;경하혈뇨위1.2%.해인군중CKD환병솔11.8%,지효솔8.2%.다인소Logistic회귀제시,CKD적최강렬위험인소위고뇨산혈증,기여의차위신결석、빈혈、당뇨병、복형비반、고혈압、년령.결론 재상해성시사구인군중,CKD환병솔위11.8%,지효솔부위8.2%.CKD적위험인소위고뇨산혈증、신결석、빈혈、당뇨병、복형비반、고혈압、년령.
Objective To investigate the prevalence, awareness and risk factors of chronic kidney disease (CKD) among community adult population in Shanghai, China, in order to provide early diagnosis and treatment of CKD, and informations for national health policy makers.Methods Two thousand five hundred and ninety six residents (≥ 18 years old) were randomly selected from community population in Changning district of Shanghai, China. They were interviewed and tested for albuminuria -morning spot urine albumin to creatinine ratio [ACR, abnormal: ≥ 17 mg/g (male), ≥25 mg/g (female)], reduced renal function-estimated GFR by abbreviated MDRD equation [abnormal: <60 ml ·rain-1 (1.73 m2)-1] and hematuria-morning spot urine dipstick confirmed by urine microscopy. The associations among demographic characteristics, healthy characteristics (e.g. diabetes and hypertension) and indicators of kidney damage were examined. The investigators and neighborhood committee were well trained. Those who had semiquantitative positive were detected again by albuminuria-morniag spot urine albumin to creatinine ratio after three months. Results Two thousand five hundred and fifty four residents with complete data were enrolled in the study. Albuminuria was detected in 6.3% of subjects, reduced renal function in 5.8%, hematuria in 1.2%. Approximately 11.8% of these subjects had at least one indicator of kidney damage. The awareness rate of CKD was 8.2%. The Logistic regression model showed that hyperuricemia, nephrolithiasis, anemia, diabetes, central obesity, hypertension and age contributed to the development of CKD. Conclusions The prevalence of CKD in community adult population in Shanghai is 11.8%, And the awareness rate of CKD is 8.2%. Hyperuricemia, nephrolithiasis, anemia, diabetes, central obesity, hypertension and age are risk factors of CKD.